Injury Division, The George Institute for Global Health, Level 5, 1 King St, Newtown, NSW, 2042, Australia.
School of Health Sciences, University of South Australia, Adelaide, SA, Australia.
Qual Life Res. 2018 Mar;27(3):619-629. doi: 10.1007/s11136-017-1724-0. Epub 2017 Oct 27.
To measure post-injury health-related quality of life (HRQoL) among hospitalised injury patients following discharge and to identify factor associated with lower HRQoL over time.
A prospective cohort study was conducted from January 2010 to October 2011 in Thai Binh province, Vietnam. Participants were 18 years or older, hospitalised for at least 1 day and normally residing in Thai Binh province. Data on demographic and injury characteristics were collected during their hospital stay. Data on HRQoL, measured by the Health Utilities Index mark 3 (HUI3), were collected in the participants' home at 1, 2, 4 and 12 months after their hospital discharge. Generalised estimating equation model was selected to examine the association of demographic and injury characteristics with HRQoL which were repeatedly measured over time.
HUI3 multi-attribute score was lowest at the first follow-up (0.52 for males, 0.28 for females). The scores significantly improved over time (increment of 0.08 or greater, p values < 0.001). Ambulation and Pain were single-attributes with scores significantly increased over time (increment of 0.05 or greater, p values < 0.001). Factors identified to be associated with lower HUI3 scores were older age (p values < 0.02 or less), more severe injury (p values = 0.05 or less) and having other illnesses (p values < 0.01).
The study provides important, and previously unreported, estimates of post-injury HRQoL in Vietnam. Even for those having the lowest levels of severity, the loss in HRQoL is significant, highlighting the importance of efforts on injury prevention and rehabilitation services.
测量出院后住院伤害患者的伤害后健康相关生活质量(HRQoL),并确定与随时间推移 HRQoL 降低相关的因素。
这是一项从 2010 年 1 月至 2011 年 10 月在越南太平省进行的前瞻性队列研究。参与者年龄在 18 岁或以上,住院至少 1 天,并且通常居住在太平省。在他们住院期间收集了人口统计学和伤害特征的数据。在参与者出院后 1、2、4 和 12 个月,在他们的家中收集了 HRQoL 数据,用健康效用指数标记 3 (HUI3)进行测量。选择广义估计方程模型来检验人口统计学和伤害特征与随时间重复测量的 HRQoL 的关联。
HUI3 多属性评分在第一次随访时最低(男性为 0.52,女性为 0.28)。分数随时间显著提高(增加 0.08 或更多,p 值<0.001)。活动能力和疼痛是单一属性,分数随时间显著增加(增加 0.05 或更多,p 值<0.001)。与 HUI3 评分较低相关的因素包括年龄较大(p 值<0.02 或更少)、伤害更严重(p 值=0.05 或更少)和患有其他疾病(p 值<0.01)。
该研究提供了越南伤害后 HRQoL 的重要且以前未报告的估计。即使对于那些严重程度最低的患者,HRQoL 的损失也很显著,突出了伤害预防和康复服务努力的重要性。