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缩窄性心包炎中缩窄性心外膜手术干预的有效性和长期结果

Effectiveness and long-term outcomes of surgical intervention for constrictive epicardium in constrictive pericarditis.

作者信息

Lee Yangsin, Naruse Yoshihiro, Tanaka Keita

机构信息

Department of Cardiac Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Department of Cardiovascular Surgery, Cardiovascular Center, Toranomon Hospital, Tokyo, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2018 Mar;66(3):137-144. doi: 10.1007/s11748-017-0854-1. Epub 2017 Oct 27.

Abstract

OBJECTIVE

Epicardial resection is considered effective in patients with constrictive pericarditis accompanied by epicardial constriction, but few publications have evaluated its long-term outcomes. The study objective was to evaluate early and late results of epicardial resection.

METHODS

A total of 22 patients with pericardiectomy for constrictive pericarditis were treated at our institution between 1989 and 2016. They were stratified by the presence or absence of constrictive epicardium and the surgical intervention performed. Group A (n = 7) included those with constrictive epicardium and epicardial resection in addition to pericardiectomy. Group B (n = 5) included those with constrictive epicardium and single pericardiectomy. Group C (n = 10) included those without constrictive epicardium and with a single pericardiectomy. Postsurgical changes were evaluated by echocardiography.

RESULTS

No significant differences were found in preoperative baseline characteristics, operative details, and operative mortality among the groups. The median postoperative follow-up was 80 months. Group A patients did not experience cardiac events, and left ventricular end-diastolic volume and stroke volume were significantly improved at late follow-up compared with before and soon after surgery. The early postsurgical parameters were significantly improved in Group C patients, but the improvements were attenuated on late follow-up. Group B patients had the highest occurrence of cardiac events and no improvement in echocardiographic parameters.

CONCLUSION

Surgical intervention in constrictive epicardium improved echocardiographic parameters and was free of cardiac events during long-term follow-up.

摘要

目的

心外膜切除术被认为对伴有心外膜缩窄的缩窄性心包炎患者有效,但很少有出版物评估其长期疗效。本研究的目的是评估心外膜切除术的早期和晚期结果。

方法

1989年至2016年期间,我们机构共治疗了22例因缩窄性心包炎而行心包切除术的患者。根据是否存在缩窄性心外膜以及所进行的手术干预进行分层。A组(n = 7)包括那些除心包切除术外还伴有缩窄性心外膜并进行心外膜切除术的患者。B组(n = 5)包括那些伴有缩窄性心外膜且仅进行心包切除术的患者。C组(n = 10)包括那些没有缩窄性心外膜且仅进行心包切除术的患者。通过超声心动图评估术后变化。

结果

各组之间在术前基线特征、手术细节和手术死亡率方面未发现显著差异。术后中位随访时间为80个月。A组患者未发生心脏事件,与手术前及术后不久相比,晚期随访时左心室舒张末期容积和每搏输出量显著改善。C组患者术后早期参数显著改善,但晚期随访时改善减弱。B组患者心脏事件发生率最高,超声心动图参数无改善。

结论

对缩窄性心外膜进行手术干预可改善超声心动图参数,且在长期随访中无心脏事件发生。

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