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用于伴有心外膜增厚的缩窄性心包炎的华夫手术的验证

Validation of Waffle procedure for constrictive pericarditis with epicardial thickening.

作者信息

Shiraishi Manabu, Yamaguchi Atsushi, Muramatsu Kenichi, Kimura Naoyuki, Yuri Koichi, Matsumoto Harunobu, Adachi Kouichi, Adachi Hideo

机构信息

Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-Ku, Saitama, 330-8503, Japan,

出版信息

Gen Thorac Cardiovasc Surg. 2015 Jan;63(1):30-7. doi: 10.1007/s11748-014-0434-6. Epub 2014 Jun 13.

Abstract

OBJECTIVE

Waffle procedure, a small grid-like incision of epicardium, is a surgical technique for constrictive pericarditis with epicardial thickening. Yet evidences to endorse this approach for improved outcomes are lacking. The aim of this study is to elucidate better surgical treatment strategy for constrictive pericarditis with epicardial thickening.

METHODS

Twenty-five patients (mean 64.1 years) who underwent pericardiectomy for constrictive pericarditis between January 1992 and July 2012 were included in this study and were classified into two groups according to the procedure they received; single total pericardiectomy (Group A, n = 17) and total pericardiectomy with the Waffle procedure (Group B, n = 8). Early and mid-term outcomes were analyzed for each group.

RESULTS

No major postoperative complications or all-cause deaths at 30 days were observed in each group. Upon discharge, postoperative echocardiography showed statistically significant increase of left ventricular end-diastolic volume (from 76.6 ± 30.3 to 91.0 ± 27.3 ml; p < 0.02) and systolic volume (from 44.4 ± 19.1 to 54.5 ± 17.3 ml; p < 0.05) in Group B than those in Group A. The 5-year cardiac event-free rate was similar between groups [83.6 ± 10.8 % for group A and 83.3 ± 15.2 % for group B (p = NS)] as well as the mean value of NYHA classification for each at the mid-term periods (1.5 for Group A and 1.3 for Group B).

CONCLUSION

Waffle procedure improved echocardiographic elements of diastolic function of patients with epicardial thickening more than did total pericardiectomy without additional compromises.

摘要

目的

华夫手术是一种在心脏外膜上做小网格状切口的手术技术,用于治疗伴有心脏外膜增厚的缩窄性心包炎。然而,目前缺乏支持该方法能改善预后的证据。本研究的目的是阐明针对伴有心脏外膜增厚的缩窄性心包炎更好的手术治疗策略。

方法

本研究纳入了1992年1月至2012年7月间因缩窄性心包炎接受心包切除术的25例患者(平均年龄64.1岁),并根据他们接受的手术方式分为两组;单纯全心包切除术(A组,n = 17)和采用华夫手术的全心包切除术(B组,n = 8)。对每组的早期和中期结果进行分析。

结果

每组均未观察到术后30天的严重并发症或全因死亡。出院时,术后超声心动图显示,B组左心室舒张末期容积(从76.6±30.3 ml增加到91.0±27.3 ml;p < 0.02)和收缩末期容积(从44.4±19.1 ml增加到54.5±17.3 ml;p < 0.05)较A组有统计学意义的增加。两组的5年无心脏事件发生率相似[A组为83.6±10.8%,B组为83.3±15.2%(p = 无统计学差异)],中期每组纽约心脏协会(NYHA)分级的平均值也相似(A组为1.5,B组为1.3)。

结论

与单纯全心包切除术相比,华夫手术能更好地改善伴有心脏外膜增厚患者舒张功能的超声心动图指标,且无额外的不良影响。

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