Davis P
J Rheumatol Suppl. 1979;5:18-24.
A review of recent studies of undesirable effects of gold salts is presented. Marrow aplasia is potentially the most serious side effect with a poor prognosis. Its prevalence is undetermined but may have been overestimated. Gold nephropathy and thrombocytopenia although more common usually have a good prognosis. Both can be satisfactorily treated without prolonged morbidity or mortality. Mucocutaneous reactions although more common are rarely of serious importance and need not necessarily prevent completion of a therapeutic course of gold salts. When indicated the side effects of gold salts can be adequately treated by cessation of therapy and use of corticosteroids. The value of chelating agents is desirable.
本文对金盐不良反应的近期研究进行了综述。再生障碍性贫血可能是最严重的副作用，预后较差。其发生率尚不确定，但可能被高估了。金肾病和血小板减少症虽然更常见，但通常预后良好。两者都可以得到满意的治疗，不会导致长期发病或死亡。皮肤黏膜反应虽然更常见，但很少具有严重意义，不一定需要中断金盐的治疗疗程。如有需要，停止治疗并使用皮质类固醇可以充分治疗金盐的副作用。螯合剂的作用是可取的。
