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各向异性通过联合不变函数对药物递送机制的影响。

Anisotropy Influences on the Drug Delivery Mechanisms by Means of Joint Invariant Functions.

作者信息

Cioca G, Bacaita E S, Agop M, Lupascu Ursulescu C

机构信息

Faculty of Medicine, Lucian Blaga University of Sibiu, Victoriei Bld. No. 10, 550024 Sibiu, Romania.

Department of Physics, "Gheorghe Asachi" Technical University of Iasi, Iasi, Romania.

出版信息

Comput Math Methods Med. 2017;2017:5748273. doi: 10.1155/2017/5748273. Epub 2017 Sep 10.

DOI:10.1155/2017/5748273
PMID:29081830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5610880/
Abstract

In the frame of Higuchi's type functionality, this paper presents the anisotropy influences on the drug delivery mechanisms through the joint invariant functions to the simultaneous actions of the two SL(2R) isomorphic groups. Then, a new equation for drug delivery mechanism, independent of the type of polymer matrix and/or drug, is proposed.

摘要

在Higuchi型功能框架下，本文通过对两个SL(2R)同构群同时作用的联合不变函数，阐述了各向异性对药物递送机制的影响。然后，提出了一个新的药物递送机制方程，该方程与聚合物基质和/或药物的类型无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5074/5610880/37f1db1bb1a0/CMMM2017-5748273.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5074/5610880/68aae1801b56/CMMM2017-5748273.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5074/5610880/37f1db1bb1a0/CMMM2017-5748273.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5074/5610880/68aae1801b56/CMMM2017-5748273.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5074/5610880/37f1db1bb1a0/CMMM2017-5748273.002.jpg

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本文引用的文献

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A multiscale mechanism of drug release from polymeric matrices: confirmation through a nonlinear theoretical model.聚合物基质中药物释放的多尺度机制：通过非线性理论模型进行验证
Phys Chem Chem Phys. 2016 Aug 21;18(31):21809-16. doi: 10.1039/c6cp02259f. Epub 2016 Jul 20.
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Tuberculosis of the oral cavity.口腔结核
Rom J Morphol Embryol. 2015;56(2):521-5.
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Carbohydrate based nanoparticles for drug delivery across biological barriers.基于碳水化合物的纳米颗粒用于跨生物屏障的药物递送。
J Biomed Nanotechnol. 2014 Sep;10(9):2107-48. doi: 10.1166/jbn.2014.1950.
4
Phases in the temporal multiscale evolution of the drug release mechanism in IPN-type chitosan based hydrogels.基于互穿网络型壳聚糖的水凝胶中药物释放机制的时间多尺度演变阶段。
Phys Chem Chem Phys. 2014 Dec 21;16(47):25896-905. doi: 10.1039/c4cp03389b. Epub 2014 Oct 30.
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Mathematical modeling of drug delivery.药物递送的数学建模。
Int J Pharm. 2008 Dec 8;364(2):328-43. doi: 10.1016/j.ijpharm.2008.09.004. Epub 2008 Sep 11.
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MECHANISM OF SUSTAINED-ACTION MEDICATION. THEORETICAL ANALYSIS OF RATE OF RELEASE OF SOLID DRUGS DISPERSED IN SOLID MATRICES.缓释药物的作用机制。分散于固体基质中的固体药物释放速率的理论分析。
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