基于铌酸钽钾电光偏转器的高相位稳定性200kHz扫频源光学相干断层扫描技术。
Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector.
作者信息
Ling Yuye, Yao Xinwen, Hendon Christine P
机构信息
Department of Electrical Engineering, Columbia University, 500 W 120th St., New York, New York 10027, USA.
出版信息
Biomed Opt Express. 2017 Jul 18;8(8):3687-3699. doi: 10.1364/BOE.8.003687. eCollection 2017 Aug 1.
Abstract
The rapid advance in swept-source optical coherence tomography (SS-OCT) technology has enabled exciting new applications in elastography, angiography, and vibrometry, where both high temporal resolution and phase stability are highly sought-after. In this paper, we present a 200 kHz SS-OCT system centered at 1321 nm by using an electro-optically tuned swept source. The proposed system's performance was fully characterized, and it possesses superior phase stability (0.0012% scanning variability and <1 ns timing jitter) that is promising for many phase-sensitive imaging applications. Biological experiments were demonstrated within human tracheobronchial ciliated epithelium where both the ciliary motion and ciliary beat frequency were successfully extracted.
摘要
扫频光学相干断层扫描（SS-OCT）技术的迅速发展，使其在弹性成像、血管造影和振动测量等领域有了令人兴奋的新应用，这些领域都对高时间分辨率和相位稳定性有很高的要求。在本文中，我们通过使用电光调谐扫频光源，展示了一个中心波长为1321 nm、频率为200 kHz的SS-OCT系统。该系统的性能得到了全面表征，具有出色的相位稳定性（扫描变化率为0.0012%，定时抖动小于1 ns），这对许多相位敏感成像应用很有前景。我们在人气管支气管纤毛上皮组织中进行了生物学实验，成功提取了纤毛运动和纤毛搏动频率。
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