Department of Ophthalmology and Visual Sciences, Neuroscience, Washington University School of Medicine, St. Louis, MO, 63108, USA.
Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, MA, 02138, USA.
BMC Biol. 2017 Oct 30;15(1):101. doi: 10.1186/s12915-017-0436-9.
Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more than direct observation of tissue. One field where this transformation is occurring is connectomics: the mapping of neural connections in large volumes of digitized brain tissue.
成像作为一种科学数据存储手段，在过去的一个世纪中经历了快速发展，从手绘图像、摄影到数字图像。直到最近，才能够获取、存储和处理足够大的数据集，以至于组织数字化实际上可以揭示出比直接观察组织更多的信息。连接组学就是这种转变正在发生的一个领域：对大量数字化脑组织中的神经连接进行映射。
