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乌干达城市人口中PrePex男性包皮环切术的长期术后结果:一项队列研究。

Long term post PrePex male circumcision outcomes in an urban population in Uganda: a cohort study.

作者信息

Galukande M, Nakaggwa F, Busisa E, Sekavuga Bbaale D, Nagaddya T, Coutinho A

机构信息

International Hospital Kampala, P.O. Box 8177, Kampala, Uganda.

International Health Sciences University, Kampala, Uganda.

出版信息

BMC Res Notes. 2017 Oct 30;10(1):522. doi: 10.1186/s13104-017-2845-9.

Abstract

OBJECTIVE

The objective of this study was to determine the long term adverse events profile at least a year after safe male circumcision.

RESULTS

A cohort study, investigating patients who had undergone a non surgical circumcision procedure called Prepex. The study variables included scar appearance and sexual experiences. Clients were contacted for a phone interview and data were collected using a questionnaire, for some, a physical examination was done. We obtained ethical committee approval. Data from 304 out of a possible 625 men were analyzed, the rest was lost to follow up. The follow up period was 12-24 months. The mean age was 28 years. Up to 97% were satisfied with the penile scar appearance and the absence of pain. There was no keloids formation, though one developed a hypertrophic scar. Participants reported improved sexual intercourse enjoyment (post circumcision). Up to 17% resumed sexual intercourse before the 6-week long mandatory abstinence period. The average self-reported healing time was 4.7 weeks. There was a high level of scar appearance satisfaction, there was no keloids formation. There was a perceived improvement of sexual enjoyment after circumcision. Trial registration ClinicalTrials. Gov Identifier: NCT02245126 (Date of registration: September 19, 2014).

摘要

目的

本研究的目的是确定安全的男性包皮环切术后至少一年的长期不良事件情况。

结果

一项队列研究,调查接受了一种名为Prepex的非手术包皮环切术的患者。研究变量包括疤痕外观和性经历。通过电话访谈联系客户,并使用问卷收集数据,部分患者还进行了体格检查。我们获得了伦理委员会的批准。对可能的625名男性中的304名的数据进行了分析,其余的失访。随访期为12至24个月。平均年龄为28岁。高达97%的人对阴茎疤痕外观和无疼痛情况感到满意。没有瘢痕疙瘩形成,不过有一人形成了增生性瘢痕。参与者报告包皮环切术后性交快感有所改善。高达17%的人在为期6周的强制禁欲期之前就恢复了性交。自我报告的平均愈合时间为4.7周。对疤痕外观的满意度很高,没有瘢痕疙瘩形成。包皮环切术后性交快感有明显改善。试验注册ClinicalTrials.gov标识符:NCT02245126(注册日期:2014年9月19日)。

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