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视觉增强靶向联合光疗治疗寻常痤疮:一例报告

Visually augmented targeted combination light therapy for acne vulgaris: a case report.

作者信息

Yazdi Alireza, Lyons Colin-William, Roberts Niamh

机构信息

Department of Primary Care and Public Health, Faculty of Public Health, Imperial College London, London, UK.

Gordano School, Portishead, Bristol, UK.

出版信息

J Med Case Rep. 2017 Oct 31;11(1):316. doi: 10.1186/s13256-017-1469-y.

DOI:10.1186/s13256-017-1469-y
PMID:29084596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5663079/
Abstract

BACKGROUND

Acne vulgaris is a common skin disease. Pharmacological modalities for treatment are proven to be efficacious but have limitations. Light therapy for acne vulgaris has shown promise in previous studies. This case report and its accompanying images show how a novel approach of visually augmented high fluence light therapy has been used to good effect.

CASE PRESENTATION

A 26-year-old Caucasian woman with acne vulgaris resistant to treatment with topical therapy underwent three sessions of combination potassium titanyl phosphate laser (532 nm)/neodymium-doped: yttrium aluminum garnet laser (1064 nm) light therapy with visually augmented narrow spot size and high fluence. A 73% reduction in total inflammatory lesions was evident 6 months after the initial treatment.

CONCLUSIONS

This case report illustrates that there may be utility in this novel approach of narrow spot size, magnification-assisted, high fluence targeted combination laser therapy for inflammatory acne.

摘要

背景

寻常痤疮是一种常见的皮肤病。治疗的药理学方法已被证明有效,但存在局限性。先前的研究表明,光疗对寻常痤疮有一定前景。本病例报告及其附带图像展示了一种视觉增强高能量光疗的新方法是如何取得良好效果的。

病例介绍

一名26岁的患有寻常痤疮且对局部治疗耐药的白种女性,接受了三次联合磷酸钛氧钾激光(532纳米)/掺钕钇铝石榴石激光(1064纳米)光疗,采用视觉增强的窄光斑尺寸和高能量。初始治疗6个月后,总炎性皮损明显减少了73%。

结论

本病例报告表明,这种窄光斑尺寸、放大辅助、高能量靶向联合激光治疗炎性痤疮的新方法可能具有实用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262c/5663079/bee2d3fde54e/13256_2017_1469_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262c/5663079/851e464f1468/13256_2017_1469_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262c/5663079/bee2d3fde54e/13256_2017_1469_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262c/5663079/851e464f1468/13256_2017_1469_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262c/5663079/bee2d3fde54e/13256_2017_1469_Fig2_HTML.jpg

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本文引用的文献

1
Light therapies for acne: abridged Cochrane systematic review including GRADE assessments.光疗法治疗痤疮:缩短版 Cochrane 系统评价,包括 GRADE 评估。
Br J Dermatol. 2018 Jan;178(1):61-75. doi: 10.1111/bjd.15495. Epub 2017 Oct 16.
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Energy-Based Devices in Treatment of Acne Vulgaris.基于能量的设备治疗寻常痤疮
Dermatol Surg. 2016 May;42(5):573-85. doi: 10.1097/DSS.0000000000000715.
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Evaluation of 532-nm KTP laser treatment efficacy on acne vulgaris with once and twice weekly applications.每周一次和每周两次应用532纳米KTP激光治疗寻常痤疮的疗效评估。
J Cosmet Laser Ther. 2011 Dec;13(6):303-7. doi: 10.3109/14764172.2011.630087.
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Comparison of a pulsed dye laser and a combined 585/1,064-nm laser in the treatment of acne vulgaris.脉冲染料激光与585/1064纳米联合激光治疗寻常痤疮的比较
Dermatol Surg. 2009 Aug;35(8):1181-7. doi: 10.1111/j.1524-4725.2008.34427.x. Epub 2009 Jan 21.
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Nonablative phototherapy for acne vulgaris using the KTP 532 nm laser.使用KTP 532纳米激光对寻常痤疮进行非剥脱性光疗。
Dermatol Surg. 2005 Oct;31(10):1290-6. doi: 10.1111/j.1524-4725.2005.31205.
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Prevalence of antibiotic-resistant propionibacteria on the skin of acne patients: 10-year surveillance data and snapshot distribution study.痤疮患者皮肤表面抗生素耐药丙酸杆菌的患病率:10年监测数据及即时分布研究
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