Mchaile Deborah N, Philemon Rune N, Kabika Sonia, Albogast Evelyn, Morijo Kikoti J, Kifaro Emmanuel, Mmbaga Blandina T
Department of Pediatrics and Child Health, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Kilimanjaro Christian Medical University College, Moshi, Tanzania.
BMC Res Notes. 2017 Oct 30;10(1):542. doi: 10.1186/s13104-017-2883-3.
Diarrhoea is a main cause of morbidity and mortality in children under 5 responsible for approximately four billion cases and 1.1 million deaths annually. In developing countries, it causes two million deaths each year. The major causative organism responsible is Rotavirus which is responsible for one-third of hospitalizations with approximately 40% mortality.
The prevalence of Rotavirus infection was 26.4% (73/277). The predominant strain of Rotavirus found was G1 21/73 (53.8%), followed by G8 9/73 (23.1%), G12 5/73 (12.8%), G9 3/73(7.7%) and G4 1/73 (2.6%). All serotypes identified were in children who had completed Rotavirus vaccination except for one who had G8 in whom the vaccine was introduced after they had completed immunizations.
The overall prevalence of rotavirus has reduced from 33.2% in 2009 to 26.4% in 2016. We have found G1 to be the predominant serotype as well as other circulating serotypes namely G4, G8, G9 and G12. Despite a reduction in prevalence, there is a need for further rotavirus surveillance in the region.
腹泻是5岁以下儿童发病和死亡的主要原因，每年约有40亿例病例和110万例死亡。在发展中国家，腹泻每年导致200万人死亡。主要致病病原体是轮状病毒，它导致三分之一的住院病例，死亡率约为40%。
轮状病毒感染的患病率为26.4%（73/277）。发现的主要轮状病毒株是G1型，共21/73（53.8%），其次是G8型，9/73（23.1%），G12型，5/73（12.8%），G9型，3/73（7.7%）和G4型，1/73（2.6%）。除了一名感染G8型的儿童在完成免疫接种后才引入疫苗外，所有鉴定出的血清型均来自已完成轮状病毒疫苗接种的儿童。
轮状病毒的总体患病率已从2009年的33.2%降至2016年的26.4%。我们发现G1型是主要血清型，以及其他流行血清型，即G4、G8、G9和G12型。尽管患病率有所下降，但该地区仍需要进一步开展轮状病毒监测。
