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本文引用的文献

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Health Effects of Overweight and Obesity in 195 Countries over 25 Years.25年间195个国家超重和肥胖对健康的影响
N Engl J Med. 2017 Jul 6;377(1):13-27. doi: 10.1056/NEJMoa1614362. Epub 2017 Jun 12.
2
A systematic review of genetic syndromes with obesity.对伴有肥胖的遗传综合征的系统评价。
Obes Rev. 2017 Jun;18(6):603-634. doi: 10.1111/obr.12531. Epub 2017 Mar 27.
3
Predicting Polygenic Obesity Using Genetic Information.利用遗传信息预测多基因肥胖症。
Cell Metab. 2017 Mar 7;25(3):535-543. doi: 10.1016/j.cmet.2017.02.013.
4
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.促肾上腺皮质激素释放激素缺乏症用促黑素细胞皮质素 4 受体激动剂治疗。
N Engl J Med. 2016 Jul 21;375(3):240-6. doi: 10.1056/NEJMoa1512693.
5
Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity.遗传学、表观遗传学和宏基因组学的最新进展揭示了人类肥胖的病理生理学。
Clin Sci (Lond). 2016 Jun 1;130(12):943-86. doi: 10.1042/CS20160136.
6
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants.1975年至2014年200个国家成人身体质量指数的趋势：对1698项基于人群测量研究的汇总分析，涉及1920万参与者。
Lancet. 2016 Apr 2;387(10026):1377-1396. doi: 10.1016/S0140-6736(16)30054-X.
7
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.利用插补变异进行遗传方差估计发现，人类身高和体重指数的缺失遗传力可忽略不计。
Nat Genet. 2015 Oct;47(10):1114-20. doi: 10.1038/ng.3390. Epub 2015 Aug 31.
8
Genetic studies of body mass index yield new insights for obesity biology.遗传研究体重指数为肥胖生物学提供了新的见解。
Nature. 2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177.
9
INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support): overview and key principles.INFORMAS（国际食物和肥胖/非传染性疾病研究、监测和行动支持网络）：概述和主要原则。
Obes Rev. 2013 Oct;14 Suppl 1:1-12. doi: 10.1111/obr.12087.
10
Variability in the heritability of body mass index: a systematic review and meta-regression.体质指数遗传度的可变性：系统评价和荟萃回归分析。
Front Endocrinol (Lausanne). 2012 Feb 28;3:29. doi: 10.3389/fendo.2012.00029. eCollection 2012.

Obesity Triggers: Sequencing the Genome Versus Sequencing the Environment.

作者信息

Bogardus Clifton, Swinburn Boyd

机构信息

Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA.

Department of Epidemiology and Biostatics, School of Population Health, The University of Auckland, Auckland, New Zealand.

出版信息

Obesity (Silver Spring). 2017 Nov;25(11):1861-1863. doi: 10.1002/oby.21985.

DOI:10.1002/oby.21985
PMID:29086501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5708890/
Abstract
摘要