Haggerty Ashley F, Hagemann Andrea, Barnett Matthew, Thornquist Mark, Neuhouser Marian L, Horowitz Neil, Colditz Graham A, Sarwer David B, Ko Emily M, Allison Kelly C
Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Obesity (Silver Spring). 2017 Nov;25 Suppl 2(Suppl 2):S102-S108. doi: 10.1002/oby.22021.
The aim of this study was to test the efficacy of technology-based weight loss interventions for endometrial cancer (EC) survivors with obesity.
EC survivors with obesity (n = 196) from three medical centers completed assessments for knowledge of obesity as a risk for EC and interest in weight management. Forty-one women were randomized to a 6-month intervention: telemedicine with Wi-Fi scales, text messaging (texting), or enhanced usual care (EUC). Changes in anthropometrics and psychosocial measures were analyzed.
One-third of survey participants lacked awareness that obesity increased the risk of EC, and 40% misclassified their body mass. There were no significant differences in weight loss across interventions (mean = -4.4 kg, SD = 6.5 kg). Telemedicine showed improvements in physical health and cancer-related body image (Ps = 0.04) compared to texting and in sexual functioning compared to EUC (P = 0.03). Total physical activity was increased in EUC compared with telemedicine (P = 0.01), and vigorous physical activity was increased in EUC compared with both interventions (P = 0.01-0.03); walking significantly increased in texting compared with telemedicine (P = 0.02).
Technology-based lifestyle interventions in EC survivors with obesity were accessible and resulted in weight loss and improved quality of life. EUC also produced weight loss, demonstrating a potential for beginning weight management with information on specific diet and exercise goals.
本研究旨在测试基于技术的减肥干预措施对肥胖的子宫内膜癌（EC）幸存者的疗效。
来自三个医疗中心的196名肥胖的EC幸存者完成了关于肥胖作为EC风险的知识以及体重管理兴趣的评估。41名女性被随机分配到为期6个月的干预组：使用Wi-Fi秤的远程医疗、短信（短信提醒）或强化常规护理（EUC）。分析人体测量学和心理社会指标的变化。
三分之一的调查参与者不知道肥胖会增加患EC的风险，40%的人对自己的体重分类错误。各干预组的体重减轻没有显著差异（平均=-4.4千克，标准差=6.5千克）。与短信提醒相比，远程医疗在身体健康和与癌症相关的身体形象方面有所改善（P=0.04），与EUC相比，在性功能方面有所改善（P=0.03）。与远程医疗相比，EUC组的总身体活动增加（P=0.01），与两种干预措施相比，EUC组的剧烈身体活动增加（P=0.01-0.03）；与远程医疗相比，短信提醒组的步行量显著增加（P=0.02）。
对肥胖的EC幸存者进行基于技术的生活方式干预是可行的，并能导致体重减轻和生活质量改善。EUC也能减轻体重，这表明通过提供特定饮食和运动目标的信息来启动体重管理具有潜力。
