Kumada Hiroaki, Takada Kenta, Sakurai Yoshinori, Suzuki Minoru, Takata Takushi, Sakurai Hideyuki, Matsumura Akira, Sakae Takeji
Faculty of Medicine, University of Tsukuba, Tennodai, Tsukuba, Ibaraki, Japan.
Proton Medical Research Center, University of Tsukuba Hospital, Amakubo, Tsukuba, Ibaraki, Japan.
Radiat Prot Dosimetry. 2018 Aug 1;180(1-4):286-290. doi: 10.1093/rpd/ncx218.
To establish boron neutron capture therapy (BNCT), the University of Tsukuba is developing a treatment device and peripheral devices required in BNCT, such as a treatment planning system. We are developing a new multimodal Monte Carlo based treatment planning system (developing code: Tsukuba Plan). Tsukuba Plan allows for dose estimation in proton therapy, X-ray therapy and heavy ion therapy in addition to BNCT because the system employs PHITS as the Monte Carlo dose calculation engine. Regarding BNCT, several verifications of the system are being carried out for its practical usage. The verification results demonstrate that Tsukuba Plan allows for accurate estimation of thermal neutron flux and gamma-ray dose as fundamental radiations of dosimetry in BNCT. In addition to the practical use of Tsukuba Plan in BNCT, we are investigating its application to other radiation therapies.
为建立硼中子俘获疗法（BNCT），筑波大学正在研发BNCT所需的治疗设备及周边设备，如治疗计划系统。我们正在开发一种基于多模态蒙特卡洛的新型治疗计划系统（开发代码：筑波计划）。筑波计划除了可用于BNCT外，还能对质子治疗、X射线治疗和重离子治疗进行剂量估算，因为该系统采用PHITS作为蒙特卡洛剂量计算引擎。关于BNCT，目前正在对该系统进行多项实际应用验证。验证结果表明，筑波计划能够准确估算作为BNCT剂量测定基础辐射的热中子通量和伽马射线剂量。除了在BNCT中实际应用筑波计划外，我们还在研究其在其他放射治疗中的应用。
