1Department of Orthopaedics, Rutgers-New Jersey Medical School, Newark, New Jersey 2Department of Biostatistics, Rutgers School of Public Health, Piscataway, New Jersey.
J Bone Joint Surg Am. 2017 Nov 1;99(21):e112. doi: 10.2106/JBJS.16.01043.
Total knee arthroplasty (TKA) is one of the most common orthopaedic procedures performed in the U.S. The purpose of this study was to develop and verify a scale to preoperatively stratify a patient's risk of being readmitted to the hospital following a TKA.
Discharge data on 433,638 patients from New York and California (derivation cohort) and 269,934 patients from Florida and Washington (validation cohort) who underwent TKA were collected from the State Inpatient Database, a part of the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality (2006 to 2011). Demographic and clinical characteristics of patients were abstracted and analyzed to develop the Readmission After Total Knee Arthroplasty (RATKA) Scale.
Overall 30-day readmission rates in the derivation and validation cohorts were 5.11% and 4.98%, respectively. The following factors were significantly associated with increased 30-day readmission rates in the derivation cohort: age of 41 to 50 years (odds ratio [OR] = 1.13), age of 71 to 80 years (OR = 1.21), age of 81 to 90 years (OR = 1.70), male sex (OR = 1.19), African-American race (OR = 1.37), "other" race/ethnicity (OR = 1.08), Medicaid payer (OR = 1.43), Medicare payer (OR = 1.27), anemia (OR = 1.19), chronic obstructive pulmonary disease (OR = 1.29), coagulopathy (OR = 1.22), congestive heart failure (OR = 1.64), diabetes (OR = 1.19), fluid and electrolyte disorder (OR = 1.25), hypertension (OR = 1.10), liver disease (OR = 1.27), renal failure (OR = 1.33), and rheumatoid arthritis (OR = 1.14). These factors were used to create the RATKA Scale. The RATKA score was then used to define 3 levels of risk for readmission: low (RATKA score of <13; 3.7% readmission rate), moderate (RATKA score of 13 to 16; 5.4% readmission rate), and high (RATKA score of >16; 7.6% readmission rate). The relative risk of readmission was 2.06 for the high-risk group compared with the low-risk group.
The RATKA Scale derived from patient data from the derivation cohort was reliably able to explain readmission variability after TKA for patients in the validation cohort at a rate of >95%. Models such as the RATKA Scale will enable identification of the risk of readmission following TKA based on a patient's risk profile prior to surgery.
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
全膝关节置换术(TKA)是美国最常见的矫形手术之一。本研究的目的是开发并验证一种术前评估 TKA 患者术后再入院风险的量表。
从纽约和加利福尼亚州的 433638 例(推导队列)和佛罗里达州和华盛顿州的 269934 例(验证队列)接受 TKA 的患者的州住院数据库中收集出院数据,该数据库是医疗保健成本和利用项目的一部分,是医疗保健研究和质量署(2006 年至 2011 年)。提取和分析患者的人口统计学和临床特征,以开发全膝关节置换术后再入院(RATKA)量表。
推导队列和验证队列的 30 天再入院率分别为 5.11%和 4.98%。以下因素与推导队列中 30 天再入院率的增加显著相关:41 至 50 岁年龄组(优势比[OR] = 1.13)、71 至 80 岁年龄组(OR = 1.21)、81 至 90 岁年龄组(OR = 1.70)、男性(OR = 1.19)、非裔美国人(OR = 1.37)、“其他”种族/民族(OR = 1.08)、医疗补助支付者(OR = 1.43)、医疗保险支付者(OR = 1.27)、贫血(OR = 1.19)、慢性阻塞性肺疾病(OR = 1.29)、凝血障碍(OR = 1.22)、充血性心力衰竭(OR = 1.64)、糖尿病(OR = 1.19)、液体和电解质紊乱(OR = 1.25)、高血压(OR = 1.10)、肝脏疾病(OR = 1.27)、肾功能衰竭(OR = 1.33)和类风湿关节炎(OR = 1.14)。这些因素被用来创建 RATKA 量表。然后使用 RATKA 评分来定义再入院的 3 个风险级别:低(RATKA 评分<13;再入院率 3.7%)、中(RATKA 评分 13 至 16;再入院率 5.4%)和高(RATKA 评分>16;再入院率 7.6%)。高危组的再入院相对风险为低危组的 2.06 倍。
从推导队列的患者数据中得出的 RATKA 量表能够可靠地解释验证队列中 TKA 后再入院的可变性,准确率超过 95%。像 RATKA 量表这样的模型将能够根据患者术前的风险状况确定 TKA 后的再入院风险。
预后 III 级。有关证据水平的完整描述,请参见作者说明。