Yoon Chung-Min, Cho Jeong-Min, Lim Kwang-Ryeol, Kim Seok-Kwun, Kim Su-Jin, Lee Keun-Cheol
Department of Plastic and Reconstructive Surgery, Dong-A University School of Medicine, Busan, Korea.
Department of Pathology, Dong-A University School of Medicine, Busan, Korea.
Arch Craniofac Surg. 2017 Sep;18(3):218-221. doi: 10.7181/acfs.2017.18.3.218. Epub 2017 Sep 26.
A solitary fibrous tumor is a relatively uncommon neoplasm that usually occurs in the pleura but occurs extremely rarely in the oral cavity. Reported herein is a rare case of a solitary fibrous tumor in the buccal cheek mucosa. A 50-year-old man visited the authors' hospital due to a buccal cheek mass whose size had increased. Excisional biopsy was done under local anesthesia. After the excisional biopsy, the patient was diagnosed to have a solitary fibrous tumor. In immunohistochemistry, the patient's solitary fibrous tumor was characterized by the expression of CD34 and CD99 on the neoplastic cells, and negativity for Bcl-2 and S-100. No recurrence or complication occurred for a period of 5 years. The growth of a primary solitary fibrous tumor in the buccal cheek mucosa is extremely rare and has been rarely reported in the South Korean medical literature. A solitary fibrous tumor must be distinguished from other spindle cell tumors. Presented herein is a case of primary solitary fibrous tumor in the buccal cheek mucosa. The relevant literature is briefly reviewed.
孤立性纤维瘤是一种相对罕见的肿瘤,通常发生于胸膜,但极少发生于口腔。本文报道了一例罕见的颊黏膜孤立性纤维瘤。一名50岁男性因颊部肿物增大就诊于作者所在医院。在局部麻醉下进行了切除活检。切除活检后,患者被诊断为孤立性纤维瘤。免疫组化显示,患者的孤立性纤维瘤表现为肿瘤细胞CD34和CD99阳性,Bcl-2和S-100阴性。5年内未出现复发或并发症。颊黏膜原发性孤立性纤维瘤的生长极为罕见,韩国医学文献中鲜有报道。孤立性纤维瘤必须与其他梭形细胞瘤相鉴别。本文介绍了一例颊黏膜原发性孤立性纤维瘤病例,并对相关文献进行了简要回顾。