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有限角度光学衍射层析成像中的广义全变差迭代约束策略

Generalized total variation iterative constraint strategy in limited angle optical diffraction tomography.

作者信息

Krauze Wojciech, Makowski Piotr, Kujawińska Małgorzata, Kuś Arkadiusz

出版信息

Opt Express. 2016 Mar 7;24(5):4924-4936. doi: 10.1364/OE.24.004924.

DOI:10.1364/OE.24.004924
PMID:29092320
Abstract

Due to incompleteness of input data inherent to Limited Angle Tomography (LAT), specific additional constraints are usually employed to suppress image artifacts. In this work we demonstrate a new two-stage regularization strategy, named Generalized Total Variation Iterative Constraint (GTVIC), dedicated to semi-piecewise-constant objects. It has been successfully applied as a supplementary module for two different reconstruction algorithms: an X-ray type solver and a diffraction-wise solver. Numerical tests performed on a detailed phantom of a biological cell under conical illumination pattern show significant reduction of axial blurring in the reconstructed refractive index distribution after GTVIC is added. Analogous results were obtained with experimental data.

摘要

由于有限角度断层扫描(LAT)固有的输入数据不完整性,通常采用特定的附加约束来抑制图像伪影。在这项工作中,我们展示了一种新的两阶段正则化策略,称为广义全变差迭代约束(GTVIC),专门用于半分段常数对象。它已成功应用于两种不同重建算法的补充模块:一种X射线型求解器和一种衍射型求解器。在锥形照明模式下对生物细胞的详细模型进行的数值测试表明,添加GTVIC后,重建的折射率分布中的轴向模糊显著减少。实验数据也得到了类似的结果。

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