Galinko Laura B, Hsu Steven H, Gauran Cosmin, Fingerhood Michael L, Pastores Stephen M, Halpern Neil A, Chawla Sanjay
Laura B. Galinko is an anesthesiology resident at New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York. At the time of this case report, Steven H. Hsu was a critical care medicine fellow and Michael L. Fingerhood was a pulmonary medicine fellow at Memorial Sloan Kettering Cancer Center, New York, New York. Cosmin Gauran is an assistant attending, Stephen M. Pastores is the critical care fellowship director, and Neil A. Halpern is the director of the Critical Care Center, and Sanjay Chawla is an associate attending in the Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center.
Am J Crit Care. 2017 Nov;26(6):491-494. doi: 10.4037/ajcc2017278.
Baking soda (sodium bicarbonate) is a common household item that has gained popularity as an alternative cancer treatment. Some have speculated that alkali therapy neutralizes the extracellular acidity of tumor cells that promotes metastases. Internet blogs have touted alkali as a safe and natural alternative to chemotherapy that targets cancer cells without systemic effects. Sodium bicarbonate overdose is uncommon, with few reports of toxic effects in humans. The case described here is the first reported case of severe metabolic alkalosis related to topical use of sodium bicarbonate as a treatment for cancer. This case highlights how a seemingly benign and readily available product can have potentially lethal consequences.
小苏打（碳酸氢钠）是一种常见的家居用品，作为一种替代性癌症治疗方法而受到欢迎。一些人推测，碱疗法可中和促进转移的肿瘤细胞的细胞外酸度。网络博客吹捧碱是一种安全天然的化疗替代物，能靶向癌细胞且无全身效应。碳酸氢钠过量并不常见，关于其对人体产生毒性作用的报道很少。此处描述的病例是首例报告的与局部使用碳酸氢钠治疗癌症相关的严重代谢性碱中毒病例。该病例凸显了一种看似无害且容易获得的产品如何可能产生潜在的致命后果。
