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血液透析中的虚弱患者:肾脏病学的新挑战——我们所在地区(巴塞罗那北部和马雷斯梅)的发病率

Frail Patient in Hemodialysis: A New Challenge in Nephrology-Incidence in Our Area, Barcelonès Nord and Maresme.

作者信息

Bancu Ioana, Graterol Fredzzia, Bonal Jorge, Fernández-Crespo Pilar, Garcia Jessica, Aguerrevere Susana, Del Castillo Domingo, Bonet Josep

机构信息

Nephrology Service, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Can Ruti Campus, Badalona, Spain.

出版信息

J Aging Res. 2017;2017:7624139. doi: 10.1155/2017/7624139. Epub 2017 Sep 28.

Abstract

INTRODUCTION

Labeling a patient as "frail" may be useful in assessing the prognosis and therapeutic approach.

OBJECTIVE

The aim of the study is to define a pattern of frailty among our dialysis population, to analyse the incidence and clinical evolution of these patients.

MATERIALS AND METHODS

We analysed a total of 320 patients with stage V chronic kidney disease (CKD) who were on hemodialysis between September 2014 and September 2015. To define a patient as frail we used the Fried phenotype model, and we added a new criteria-dialysis session length longer than 12 hours/week.

RESULTS

5.6% of the 320 patients were frail. We found statistically significant differences regarding body mass index (BMI), hemoglobin (Hgb), and serum albumin, as well as the ability to perform the basic activities of daily living ( < 0.005), ability to ambulate ( = 0.01) and perform transfers ( < 0.005). We found statistically significant differences between the two groups in terms of hospital admissions ( = 0.005) and mortality ( < 0.005).

CONCLUSION

5.6% of the study population were frail, with lower BMI, serum albumin and hemoglobin, lower capacity for basic activities of daily living, ambulation, and transference, as well as higher morbidity and mortality.

摘要

引言

将患者标记为“虚弱”可能有助于评估预后和治疗方法。

目的

本研究的目的是确定我们透析人群中的虚弱模式,分析这些患者的发病率和临床演变。

材料与方法

我们分析了2014年9月至2015年9月期间接受血液透析的320例Ⅴ期慢性肾脏病(CKD)患者。为了将患者定义为虚弱,我们使用了弗里德表型模型,并增加了一个新的标准——透析疗程长度超过12小时/周。

结果

320例患者中有5.6%为虚弱患者。我们发现,在体重指数(BMI)、血红蛋白(Hgb)和血清白蛋白方面,以及在进行日常生活基本活动的能力(<0.005)、行走能力(=0.01)和转移能力(<0.005)方面存在统计学显著差异。两组在住院率(=0.005)和死亡率(<0.005)方面存在统计学显著差异。

结论

研究人群中有5.6%为虚弱患者,他们的BMI、血清白蛋白和血红蛋白较低,日常生活基本活动、行走和转移能力较低,发病率和死亡率较高。

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