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慢性鼻窦炎鼻窦手术后的嗅觉变化过程

Course of olfaction after sinus surgery for chronic rhinosinusitis.

作者信息

Haxel Boris R, Boessert Patrick, Weyer-Elberich Veronika, Fruth Kai

机构信息

Department of Otolaryngology Head and Neck Surgery, AMEOS Klinikum Haldensleben Germany.

the Department of Otolaryngology, Head and Neck Surgery University Medical Center of the Johannes Gutenberg University Mainz Germany.

出版信息

Laryngoscope Investig Otolaryngol. 2017 Sep 25;2(5):269-275. doi: 10.1002/lio2.109. eCollection 2017 Oct.

Abstract

BACKGROUND

The influence of surgery on olfaction in patients who suffer from chronic rhinosinusitis (CRS) is still not fully understood. Most particularly, the time course of the recovery is poorly studied.

METHODS

The prospective study describes the results of the Sniffin' Sticks identification test in 41 subjects before (V1), 2 weeks after (V2), and 6 months after (V3) endonasal sinus surgery (ESS). Influencing factors (gender, revision surgery, nasal polyposis, and initial olfactory score) on the changes of the smell testing were evaluated.

RESULTS

The whole cohort showed a significant improvement in Identification scores, from 8.63 to 10.24 after 2 weeks and to 10.68 after 6 months. Patients with nasal polyps revealed a similar increase in the identification test at V3 (+2.17 compared to +1.89 in those without polyps) but not at V2 (+1.30 compared to 2.00). The initial classification of olfaction was the only significant influencing factor. Patients who showed initially anosmic results improved (+4.87 at V2 and +4.73 at V3), as did patients in the hyposmic group (+0.58 resp. +1.42). Forty-four percent of the patients reached an improvement with regard to their diagnostic group.

CONCLUSIONS

This study of the evaluation of the sense of smell after ESS exhibits an improvement of olfaction already 2 weeks after surgery, which is stable for 6 months. CRSwNP and CRSsNP patients showed similar improvements of olfaction, although the recovery was slower in CRSwNP patients.

LEVEL OF EVIDENCE

2b.

摘要

背景

手术对慢性鼻窦炎(CRS)患者嗅觉的影响仍未完全明确。尤其是,恢复的时间进程研究较少。

方法

这项前瞻性研究描述了41名受试者在鼻内鼻窦手术(ESS)前(V1)、术后2周(V2)和术后6个月(V3)时进行的嗅觉棒识别测试结果。评估了嗅觉测试变化的影响因素(性别、翻修手术、鼻息肉和初始嗅觉评分)。

结果

整个队列的识别分数有显著改善,术后2周从8.63提高到10.24,术后6个月提高到10.68。鼻息肉患者在V3时识别测试有类似增加(与无息肉患者的+1.89相比为+2.17),但在V2时没有(与2.00相比为+1.30)。嗅觉的初始分类是唯一显著的影响因素。最初表现为嗅觉丧失的患者有所改善(V2时提高+4.87,V3时提高+4.73),嗅觉减退组的患者也是如此(分别提高+0.58和+1.42)。44%的患者在诊断分组方面有所改善。

结论

这项关于ESS后嗅觉评估的研究表明,术后2周嗅觉即有改善,且在6个月内保持稳定。CRSwNP和CRSsNP患者的嗅觉改善相似,尽管CRSwNP患者的恢复较慢。

证据级别

2b。

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