Department of Otolaryngology, Head and Neck Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Germany.
Clin Otolaryngol. 2011 Feb;36(1):17-23. doi: 10.1111/j.1749-4486.2011.02261.x.
To determine the efficacy of the nasal airflow-inducing manoeuvre (NAIM) as a method for olfactory rehabilitation in laryngectomees by the means of the Sniffin' Sticks test.
Prospective open interventional trial.
Tertiary academic hospital.
Thirty-seven patients after laryngectomy have been screened and 25 patients have been included into the study. The participant's sense of smell was tested with the Sniffin' Sticks test before and after learning the nasal airflow inducing manoeuvre. The individual level of threshold, discrimination and identification (TDI) was determined and the individual threshold, discrimination and identification score was used to classify the patients as being anosmic, hyposmic or normosmic.
The primary endpoint was the change of the threshold, discrimination and identification score before and after learning the nasal airflow inducing manoeuvre. The secondary endpoint was a change in the diagnostic group (normosmic, hyposmic and anosmic) after learning of the nasal airflow inducing manoeuvre.
There was a statistically significant increase in the total threshold, discrimination and identification score (P < 0.001) and the three sub-scores (P ≤ 0.02) before and after the learning of the nasal airflow inducing manoeuvre. Patients gained seven points on average in the threshold, discrimination and identification score. Twenty of 25 patients showed an increase of five or more point in the threshold, discrimination and identification score. In the classification of the smell ability, 15 of 25 patients showed a change to a higher class (hyposmic to normosmic or from anosmic to hyposmic or normosmic).
The nasal airflow inducing manoeuvre is a method for the successful rehabilitation of the sense of smell in laryngectomees. The evaluation with the Sniffin' Sticks tests showed a clinically relevant increase of olfaction in 80% of patients. The teaching of the nasal airflow inducing manoeuvre should be included in post-laryngectomy rehabilitation programmes.
通过嗅觉测试(Sniffin' Sticks 测试),评估经鼻气流刺激法(NAIM)对喉切除术后患者嗅觉康复的疗效。
前瞻性开放干预性试验。
三级学术医院。
对 37 例喉切除术后患者进行了筛查,其中 25 例患者被纳入研究。在学习经鼻气流刺激法前后,使用嗅觉测试(Sniffin' Sticks 测试)对参与者的嗅觉进行了测试。分别测定了个体的阈值、辨别力和识别力(TDI),并将个体阈值、辨别力和识别力评分用于将患者分类为嗅觉丧失、嗅觉减退或嗅觉正常。
主要终点为学习经鼻气流刺激法前后阈值、辨别力和识别力评分的变化。次要终点为学习经鼻气流刺激法后诊断分组(嗅觉正常、嗅觉减退和嗅觉丧失)的变化。
学习经鼻气流刺激法前后,总阈值、辨别力和识别力评分(P < 0.001)以及三个亚评分(P ≤ 0.02)均有统计学显著增加。患者的阈值、辨别力和识别力评分平均增加了 7 分。25 例患者中有 20 例患者的阈值、辨别力和识别力评分增加了 5 分或更多。在嗅觉能力的分类中,25 例患者中有 15 例显示出向更高等级的变化(嗅觉减退变为嗅觉正常或嗅觉丧失变为嗅觉减退或嗅觉正常)。
经鼻气流刺激法是喉切除术后嗅觉康复的有效方法。Sniffin' Sticks 测试评估显示,80%的患者嗅觉有临床相关的改善。经鼻气流刺激法的教学应纳入喉切除术后康复计划中。