Mumtaz Shazia, Wang Li-Sheng, Hussain Syed Zajif, Abdullah Muhammad, Huma Zille, Iqbal Zafar, Creran Brian, Rotello Vincent M, Hussain Irshad
Department of Chemistry, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), DHA, Lahore Cantt - 54792, Lahore, Pakistan.
Chem Commun (Camb). 2017 Nov 14;53(91):12306-12308. doi: 10.1039/c7cc07149c.
We report a simple and economical colorimetric bacterial sensing strategy with catalytic amplification using dopamine-capped iron oxide (Dop-FeO) nanoparticles. These nanoparticles catalyse the oxidation of a chromogenic substrate in the presence of HO into a green colored product. The catalytic activity of the nanoparticles is inhibited in the presence of bacteria, providing naked eye detection of bacteria at 10 cfu mL and by spectrophotometric detection down to 10 cfu mL.
我们报道了一种简单且经济的比色细菌传感策略,该策略利用多巴胺包覆的氧化铁(Dop-FeO)纳米颗粒进行催化放大。这些纳米颗粒在过氧化氢存在的情况下催化显色底物氧化成绿色产物。在细菌存在时,纳米颗粒的催化活性受到抑制,可通过肉眼在10 cfu/mL下检测细菌,通过分光光度法检测低至10 cfu/mL。