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一头圈养的幼年亚洲象感染1型大象嗜内皮疱疹病毒的亚临床感染

Subclinical infection of a young captive Asian elephant with elephant endotheliotropic herpesvirus 1.

作者信息

Azab Walid, Damiani Armando Mario, Ochs Andreas, Osterrieder Nikolaus

机构信息

Institut für Virologie, Robert von Ostertag-Haus, Zentrum für Infektionsmedizin, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163, Berlin, Germany.

Instituto de Medicina y Biología Experimental de Cuyo IMBECU, CCT Mendoza-CONICET, Área de Química Biológica, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.

出版信息

Arch Virol. 2018 Feb;163(2):495-500. doi: 10.1007/s00705-017-3628-2. Epub 2017 Nov 1.

DOI:10.1007/s00705-017-3628-2
PMID:29094239
Abstract

Elephant endotheliotropic herpesviruses (EEHVs) are a continuous threat for young Asian elephants. We report a laboratory-confirmed infection of a 5-year-old female Asian elephant (AZ_2016) in the Berlin Zoologischer Garten. Initially, high EEHV-1 loads were detected in trunk swabs obtained from the young elephant during routine screening. The animal showed no clinical signs except for slight irritability. EEHV-1 was continuously shed for almost one year, with fluctuations in viral load from time to time. Our investigations highlight the continuous threat of EEHV-1 to young captive Asian elephants and stress the importance of routine monitoring of captive elephants to allow early detection of infection.

摘要

大象内皮嗜性疱疹病毒(EEHVs)对亚洲象幼崽构成持续威胁。我们报告了柏林动物园一头5岁雌性亚洲象(AZ_2016)经实验室确诊的感染病例。最初,在对这头幼象进行常规筛查时,从其象鼻拭子中检测到高浓度的EEHV-1。这头大象除了有轻微易怒外,没有表现出任何临床症状。EEHV-1持续排出近一年,病毒载量时有波动。我们的研究突出了EEHV-1对圈养亚洲象幼崽的持续威胁,并强调了对圈养大象进行常规监测以实现早期感染检测的重要性。

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