Sturdy K A, Beastall R H, Grisius R J, Oatis G W
Oral Surg Oral Med Oral Pathol. 1979 Nov;48(5):418-20. doi: 10.1016/0030-4220(79)90072-0.
Hereditary angioedema is a condition which should be approached with caution and concern for the patient. The fact that the disease can be fatal cannot be overemphasized. The routine medical history should include questions aimed at identifying these patients. If the angioedema patient is to be treated, provisions must be made for maintenance of an adequate airway. This should include intubation if deemed necessary, and the practitioner should be prepared for a tracheostomy. Close observation following extubation is indicated. A case report in which the patient was controlled with danazol, a synthetic androgen, has been presented. The primary advantage of this drug is a decrease in the various side effects which have been associated with other therapeutic agents used previously in the treatment of hereditary angioedema.
遗传性血管性水肿是一种需要谨慎对待并关注患者的病症。这种疾病可能致命,这一点再怎么强调都不为过。常规病史询问应包括旨在识别这些患者的问题。如果要对血管性水肿患者进行治疗,必须做好维持气道通畅的准备。这应包括在必要时进行插管,并且从业者应做好气管切开术的准备。拔管后需密切观察。本文呈现了一例使用合成雄激素达那唑控制病情的病例报告。这种药物的主要优点是减少了先前用于治疗遗传性血管性水肿的其他治疗药物所伴随的各种副作用。