Prion and Prion-like Diseases in Humans: Poster Abstracts.
出版信息
Prion. 2013 Apr/May;7(sup1):54-80. doi: 10.4161/pri.24865.
Abstract
摘要
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本文引用的文献
1
Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice.具有抗朊病毒活性的 2-氨基噻唑类药物在小鼠体内的药代动力学和代谢。
Pharm Res. 2013 Apr;30(4):932-50. doi: 10.1007/s11095-012-0912-4. Epub 2013 Feb 16.
2
Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice.朊病毒感染小鼠海马 CA1 神经元转录时间动态揭示了发病机制的早期机制。
PLoS Pathog. 2012;8(11):e1003002. doi: 10.1371/journal.ppat.1003002. Epub 2012 Nov 8.
3
Coexistence of protease sensitive and resistant prion protein in 129VV homozygous sporadic Creutzfeldt-Jakob disease: a case report.129VV纯合子散发性克雅氏病中蛋白酶敏感和抗性朊病毒蛋白共存：一例报告
J Med Case Rep. 2012 Oct 11;6:348. doi: 10.1186/1752-1947-6-348.
4
Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit.将朊病毒假说推广到其他神经退行性疾病：不完全契合。
J Toxicol Environ Health A. 2011;74(22-24):1433-59. doi: 10.1080/15287394.2011.618967.
5
Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion.使用实时液流诱导转换技术灵敏且特异地检测散发性克雅氏病脑部朊病毒蛋白。
J Gen Virol. 2012 Feb;93(Pt 2):438-449. doi: 10.1099/vir.0.033365-0. Epub 2011 Oct 26.
6
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.活细胞中超氧化物歧化酶 1 错误折叠的分子间传递。
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16398-403. doi: 10.1073/pnas.1102645108. Epub 2011 Sep 19.
7
Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein.蛋白酶体功能障碍和内质网应激通过分泌途径增强朊病毒蛋白聚集物的运输，并增加病理性朊病毒蛋白的积累。
J Biol Chem. 2011 Sep 30;286(39):33942-53. doi: 10.1074/jbc.M111.272617. Epub 2011 Aug 11.
8
Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity.发现 6-取代吲哚-3-乙氧酰胺类化合物作为先导抗朊病毒药物，具有增强的细胞系活性、改善的微粒体稳定性和低毒性。
Eur J Med Chem. 2011 Sep;46(9):4125-32. doi: 10.1016/j.ejmech.2011.06.013. Epub 2011 Jun 17.
9
Heparin enhances the cell-protein misfolding cyclic amplification efficiency of variant Creutzfeldt-Jakob disease.肝素增强变异型克雅氏病的细胞-蛋白错误折叠循环扩增效率。
Neurosci Lett. 2011 Jul 8;498(2):119-23. doi: 10.1016/j.neulet.2011.04.072. Epub 2011 May 5.
10
Peripheral reduction of β-amyloid is sufficient to reduce brain β-amyloid: implications for Alzheimer's disease.外周β-淀粉样蛋白减少足以减少脑内β-淀粉样蛋白：对阿尔茨海默病的影响。
J Neurosci Res. 2011 Jun;89(6):808-14. doi: 10.1002/jnr.22603. Epub 2011 Mar 3.
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