Choi Min Joo, Song Joon Young, Noh Ji Yun, Yoon Jin Gu, Lee Saem Na, Heo Jung Yeon, Yoon Jae Won, Jo Yu Mi, Cheong Hee Jin, Kim Woo Joo
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine Asian Pacific Influenza Institute, Seoul Division of Infectious Diseases, Department of Internal Medicine, Chungbuk National University College of Medicine Division of Infectious Diseases, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Republic of Korea.
Medicine (Baltimore). 2017 Nov;96(44):e8429. doi: 10.1097/MD.0000000000008429.
Pneumonia is a leading cause of hospitalization and mortality worldwide. Despite recognition of the importance of community-acquired pneumonia (CAP) in adults, limited epidemiologic information is available in South Korea. This study aimed to evaluate the disease burden of hospitalized CAP in adults aged ≥19 years and its epidemiologic trend using Health Insurance and Review Assessment (HIRA) data.This is a retrospective study using the HIRA database from year 2009 to 2013. We estimated the incidence rate and direct medical cost of hospitalized CAP in adults aged ≥19 years in South Korea. These were further analyzed with respect to age and underlying medical conditions.During 2009 to 2013, 1216,916 hospitalizations were recorded. On average, the annual age-adjusted incidence rate of hospitalized CAP was 626 per 100,000 persons, with the rate increasing with age. When stratified by age- and risk groups, elderly people ≥75 years showed the highest incidence rate of hospitalized CAP over 5-year study periods. With respect to the risk groups based on underlying medical conditions, incidence rate ratios were 2.04 to 5.86 for the high-risk group versus the low-risk group and 1.28 to 5.49 for the moderate-risk group versus the low-risk group. Overall, mean direct medical cost for hospitalized CAP was 1851 USD per capita during the 5-year period: 1263 USD in the low-risk group, 2353 USD in the moderate-risk group, and 2841 USD in the high-risk group.This study shows that the incidence and medical cost of hospitalized CAP were consistently high over the 5-year study period. In particular, elderly people and adults with underlying medical conditions were at increased risk for hospitalized CAP.
肺炎是全球住院和死亡的主要原因。尽管人们认识到社区获得性肺炎（CAP）在成人中的重要性，但韩国的流行病学信息有限。本研究旨在利用健康保险审查评估（HIRA）数据评估≥19岁成人住院CAP的疾病负担及其流行病学趋势。
这是一项使用2009年至2013年HIRA数据库的回顾性研究。我们估计了韩国≥19岁成人住院CAP的发病率和直接医疗费用，并按年龄和基础疾病进行了进一步分析。
2009年至2013年期间，共记录了1216916例住院病例。平均而言，住院CAP的年龄调整后年发病率为每10万人626例，且发病率随年龄增长而增加。按年龄和风险组分层时，在5年研究期间，≥75岁的老年人住院CAP发病率最高。就基于基础疾病的风险组而言，高危组与低危组的发病率比值为2.04至5.86，中危组与低危组的发病率比值为1.28至5.49。总体而言，5年期间住院CAP的人均直接医疗费用为1851美元：低危组为1263美元，中危组为2353美元，高危组为2841美元。
本研究表明，在5年研究期间，住院CAP的发病率和医疗费用一直居高不下。特别是，老年人和有基础疾病的成年人住院CAP的风险增加。
