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成人期与儿童期自杀意念和行为的关联:一项前瞻性、纵向分析。

Adult Associations of Childhood Suicidal Thoughts and Behaviors: A Prospective, Longitudinal Analysis.

机构信息

Duke University Medical Center, Durham, NC.

Duke University Medical Center, Durham, NC.

出版信息

J Am Acad Child Adolesc Psychiatry. 2017 Nov;56(11):958-965.e4. doi: 10.1016/j.jaac.2017.08.015. Epub 2017 Sep 15.

Abstract

OBJECTIVE

Suicidal thoughts and behavior (STBs) have their peak period of onset in adolescence, but little is known about how such behavior is associated with later functioning. The aim of this study is to test whether childhood STBs are related to adult psychiatric, suicidal, and functional outcomes.

METHOD

This is a prospective, population-based community study of 1,420 participants assessed with structured interviews up to 7 times in childhood/adolescence (ages 9-16 years; 6,674 observations) for STBs including passive and active ideation, plans, and attempts. Participants were then assessed 4 times in young adulthood (ages 19, 21, 24, and 30 years; 4,556 observations of 1,273 participants) for psychiatric diagnoses, STBs, and functional outcomes.

RESULTS

By age 16 years, 7.0% of participants had reported some type of STBs, with 3.9% reporting an attempt. Both ideation only and suicide attempts were associated with higher levels of anxiety disorders and STBs in adulthood, as well as poor functioning across financial, health, risky/illegal, and social domains. These observed effects generally were attenuated after adjusting for other psychiatric and psychosocial factors that predict childhood STBs (particularly maltreatment, depression, and disruptive behavior disorders). The exception was adult suicidal behavior, which was predicted by both childhood ideation and attempts, even in the fully adjusted model. Children and adolescents with STBs were more likely to have had a disrupted transition to adulthood.

CONCLUSION

Childhood STBs are a marker for a multitude of poor psychiatric and functional outcomes in adulthood, but these effects are largely accounted for by other factors. In contrast, childhood STBs are a robust risk factor for adult suicidal thoughts and behavior.

摘要

目的

自杀意念和行为(STBs)在青少年时期达到发病高峰,但人们对这种行为如何与以后的功能相关知之甚少。本研究旨在检验儿童时期的 STB 是否与成年期的精神疾病、自杀和功能结果有关。

方法

这是一项前瞻性的、基于人群的社区研究,共纳入 1420 名参与者,在儿童/青少年时期(9-16 岁;6674 次观察)使用结构化访谈进行评估,评估内容包括被动和主动的意念、计划和尝试自杀。然后,参与者在成年早期(19、21、24 和 30 岁;1273 名参与者中的 4556 次观察)进行了 4 次评估,评估内容包括精神疾病诊断、STB 和功能结果。

结果

到 16 岁时,7.0%的参与者报告了某种类型的 STB,其中 3.9%的参与者报告了自杀尝试。只有意念和自杀尝试都与成年期更高水平的焦虑障碍和 STB 以及财务、健康、危险/非法和社会领域的不良功能有关。这些观察到的影响在调整了其他预测儿童 STB 的精神和心理社会因素(特别是虐待、抑郁和破坏性行为障碍)后通常会减弱。但成年期的自杀行为除外,即使在完全调整的模型中,它也同时受到儿童期意念和尝试的预测。有 STB 的儿童和青少年更有可能经历成年期的不良过渡。

结论

儿童时期的 STB 是成年期多种不良精神和功能结果的一个标志,但这些影响在很大程度上被其他因素所解释。相比之下,儿童时期的 STB 是成年期自杀意念和行为的一个强有力的风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/6501553/636662b8e669/nihms-912552-f0001.jpg

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