Washington University School of Medicine in St. Louis, Missouri.
Washington University School of Medicine in St. Louis, Missouri.
J Am Acad Child Adolesc Psychiatry. 2022 May;61(5):676-685. doi: 10.1016/j.jaac.2021.08.020. Epub 2021 Sep 7.
Suicidal thoughts and behaviors (STBs) represent a significant and escalating public health concern in youth. Evidence that STBs can emerge in the preschool years suggests that some pathways leading to clinically significant STBs begin early in life.
This prospective longitudinal study examined the developmental trajectories of STBs in children from ages 3 to 17, oversampled for preschool-onset depression.
Three unique trajectories of STBs across childhood and adolescence were identified: low class (n = 273) characterized by low rates of STBs, early-persistent class (n = 21) characterized by steadily increasing STBs, and late-onset class (n = 21) characterized by low rates of STBs through age 10 followed by a dramatic increase from ages 11 to 14 years. Preschool measures of depression symptoms, externalizing symptoms, impulsivity, and lower income relative to needs were associated with both high-risk STB classes. Both high-risk STB classes reported greater functional impairment, more externalizing symptoms, and more cumulative stressful life events in adolescence relative to the low class; the late-onset class also reported poorer academic functioning relative to both the early-persistent and low classes.
A significant minority of this prospectively followed group of preschool children evidenced STBs by and/or after age 10. Although relatively rare before age 10, approximately half of the children who experienced STBs in adolescence first exhibited STBs in early childhood and comprised a trajectory suggesting increasing STBs. In contrast, approximately half of children first exhibited STBs in early adolescence. Early screening and identification of at-risk youth during both preschool and late childhood is important for early intervention regarding STBs.
自杀念头和行为(STB)是青少年中一个严重且不断加剧的公共卫生问题。有证据表明,STB 可能在学龄前出现,这表明一些导致临床显著 STB 的途径早在生命早期就开始了。
本前瞻性纵向研究调查了 3 至 17 岁儿童的 STB 发展轨迹,该研究对学龄前起病的抑郁症进行了抽样。
确定了儿童期和青春期 STB 的三种独特轨迹:低类(n=273)的 STB 率较低,早期持续类(n=21)的 STB 率稳步增加,以及晚发性类(n=21)的 STB 率在 10 岁前较低,随后在 11 岁至 14 岁之间急剧增加。学龄前的抑郁症状、外化症状、冲动和相对于需求的低收入与高风险 STB 类都有关。与低风险 STB 类相比,高风险 STB 类在青少年时期报告了更多的功能障碍、更多的外化症状和更多的累积生活压力事件;晚发性类还报告了相对较差的学业功能,与早期持续类和低类相比。
在这个前瞻性随访的学龄前儿童群体中,有相当一部分儿童在 10 岁之前或之后表现出 STB。虽然在 10 岁之前相对较少见,但在青春期经历 STB 的儿童中,约有一半的儿童首先在幼儿期表现出 STB,并表现出 STB 增加的轨迹。相比之下,大约一半的儿童首先在青春期早期表现出 STB。在学龄前和晚童年期对高危青少年进行早期筛查和识别,对于 STB 的早期干预很重要。