De Carvalho M, De Carvalho D, Trzmielina S, Lopes J M, Hansen T W
Clínica Perinatal Laranjeiras, Rio de Janeiro, Brazil.
Acta Paediatr. 1999 Jul;88(7):768-71. doi: 10.1080/08035259950169071.
Jaundice is a common reason for therapeutic intervention in newborn infants and phototherapy is effective treatment if enough light energy is delivered to a skin surface area of sufficient size. Narrow spectrum blue light is superior to white light, but in developing countries fluorescent blue lamps often have to be imported and are much more expensive than white lamps. We developed a phototherapy unit in which seven daylight fluorescent tubes are placed immediately under the floor of a transparent plexiglass crib. The efficacy of this unit, delivering approximately 19 microW/cm2/nm, was compared with that of two conventional phototherapy units using overhead lamps placed 35 cm above the infants. One unit used daylight fluorescent tubes and delivered approximately 4 microW/cm2/nm, the other unit used special blue fluorescent tubes and delivered approximately 22 microW/cm2/nm. Fifty-one infants were included in the analyses, all of them breastfed on demand. Serum bilirubin levels were determined spectrophotometrically at 0, 12 and 24 h. The decrement in serum bilirubin concentrations was significantly greater in infants undergoing phototherapy with the new device or with special blue lamps compared to conventional overhead daylight lamps (p < 0.001 both at 12 and at 24 h). We conclude that highly efficient phototherapy may be delivered with daylight fluorescent lamps placed in very close proximity to the patient. Thus, lack of access to expensive imported special blue lamps does not preclude delivery of effective phototherapy in developing countries.
黄疸是新生儿进行治疗干预的常见原因,若能将足够的光能传递到足够大的皮肤表面积,光疗就是一种有效的治疗方法。窄谱蓝光优于白光,但在发展中国家,荧光蓝光灯往往需要进口,且比白光灯昂贵得多。我们开发了一种光疗设备,其中七支日光荧光灯管直接放置在透明有机玻璃婴儿床的地板下方。将该设备(提供约19微瓦/平方厘米/纳米的能量)的疗效与另外两种传统光疗设备进行了比较,这两种传统设备使用的是置于婴儿上方35厘米处的顶灯。一种设备使用日光荧光灯管,提供约4微瓦/平方厘米/纳米的能量,另一种设备使用特殊蓝色荧光灯管,提供约22微瓦/平方厘米/纳米的能量。51名婴儿纳入分析,所有婴儿均按需母乳喂养。在0、12和24小时用分光光度法测定血清胆红素水平。与传统顶灯日光灯管相比,使用新设备或特殊蓝色灯管进行光疗的婴儿血清胆红素浓度的下降幅度显著更大(12小时和24小时时p均<0.001)。我们得出结论,将日光荧光灯管放置在非常靠近患者的位置可以实现高效光疗。因此,在发展中国家,无法获得昂贵的进口特殊蓝光灯并不妨碍提供有效的光疗。