University of Maryland School of Medicine, Baltimore, MD, United States.
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, United States.
Resuscitation. 2018 Jan;122:121-125. doi: 10.1016/j.resuscitation.2017.10.027. Epub 2017 Oct 31.
Cardiac arrest in peripartum patients is a rare but devastating event; reported rates in the literature range from 0.019% to 0.0085%. In the general population, a well-described complication of cardiopulmonary resuscitation (CPR), liver laceration and injury, is reported at a rate of between 0.5-2.9% after CPR. Liver laceration rate among peripartum patients receiving CPR has not been well-studied. We sought to find the rate of liver lacerations in the peripartum population associated with CPR, with the hypothesis that the rate would be higher than in the general population.
We identified pregnancies complicated by cardiac arrest by performing a retrospective medical record review from 2011 to 2016 at a single tertiary referral hospital. We then compared the rate of liver lacerations in this group to the rate in the general population as found in the literature.
Eleven of 9408 women in the peripartum period suffered cardiac arrest. Return of spontaneous circulation occurred in seven of eleven (64%) women. Three of these seven women suffered clinically significant liver laceration (43%). Overall mortality rate among women suffering cardiac arrest was 82% (9/11).Even after return of spontaneous circulation, the mortality rate was 72%(5/7) including two of three women suffering liver laceration.
Based on a small retrospective study, liver lacerations requiring intervention occurred in 43% of gravidas patients that survived CPR, and is significantly higher than published rates (0.6-2.1%) for the general patient population. Further studies are indicated to determine the incidence of liver injury after peripartum CPR.
围产期患者心搏骤停较为罕见,但后果严重;文献报道的发生率范围为 0.019%至 0.0085%。在普通人群中,心肺复苏(CPR)后肝破裂和损伤是一种描述明确的并发症,其发生率为 0.5-2.9%。CPR 治疗围产期患者的肝破裂发生率尚未得到很好的研究。我们旨在发现与 CPR 相关的围产期人群中肝破裂的发生率,假设其发生率高于普通人群。
我们通过对一家三级转诊医院 2011 年至 2016 年的病历进行回顾性研究,确定了围产期合并心搏骤停的妊娠。然后,我们将该组患者的肝破裂发生率与文献中的普通人群发生率进行比较。
11 例围产期妇女发生心搏骤停,11 例中有 7 例(64%)妇女自主循环恢复。这 7 例中有 3 例(43%)发生了临床显著的肝破裂。心搏骤停妇女的总死亡率为 82%(9/11)。即使自主循环恢复后,死亡率仍为 72%(5/7),其中 2 例肝破裂患者。
基于一项小型回顾性研究,存活 CPR 治疗的孕妇患者中,有 43%发生了需要干预的肝破裂,明显高于普通患者人群(0.6-2.1%)的报道发生率。需要进一步研究以确定围产期 CPR 后肝损伤的发生率。