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本文引用的文献

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J Biol Methods. 2019 Mar 15;6(1):e110. doi: 10.14440/jbm.2019.276. eCollection 2019.
2
Molecular epidemiology of tuberculosis in Tasmania and genomic characterisation of its first known multi-drug resistant case.塔斯马尼亚结核病的分子流行病学及其首例已知耐多药病例的基因组特征分析
PLoS One. 2018 Feb 21;13(2):e0192351. doi: 10.1371/journal.pone.0192351. eCollection 2018.
3
Molecular epidemiology of multi- and extensively-drug-resistant Mycobacterium tuberculosis in Ireland, 2001-2014.2001-2014 年爱尔兰耐多药和广泛耐药结核分枝杆菌的分子流行病学研究。
J Infect. 2018 Jan;76(1):55-67. doi: 10.1016/j.jinf.2017.10.002. Epub 2017 Oct 12.
4
TGS-TB: Total Genotyping Solution for Mycobacterium tuberculosis Using Short-Read Whole-Genome Sequencing.TGS-TB:利用短读长全基因组测序技术的结核分枝杆菌全基因分型解决方案
PLoS One. 2015 Nov 13;10(11):e0142951. doi: 10.1371/journal.pone.0142951. eCollection 2015.
5
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain.耐多药结核分枝杆菌暴发菌株四十年来的传播情况
Nat Commun. 2015 May 11;6:7119. doi: 10.1038/ncomms8119.
6
PhyResSE: a Web Tool Delineating Mycobacterium tuberculosis Antibiotic Resistance and Lineage from Whole-Genome Sequencing Data.PhyResSE:一种从全基因组测序数据中描绘结核分枝杆菌抗生素耐药性和谱系的网络工具。
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Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in New Zealand.新西兰首例广泛耐药结核分枝杆菌分离株的基因组序列草图
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来自尼泊尔的一株广泛耐药结核分枝杆菌分离株的基因组序列草图

Draft Genome Sequence of an Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis from Nepal.

作者信息

Gautam Sanjay S, Leong Kelvin W C, Pradhan Manoj, Singh Y Ibotomba, Rajbhandari Sagar K, Ghimire Gokarna R, Adhikari Krishna, Shrestha Uma, Chaudhary Raina, Ghimire Gyanendra, Khadka Sundar, O'Toole Ronan F

机构信息

School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.

School of Molecular Sciences, College of Science, Health and Engineering, La Trobe University, Victoria, Australia.

出版信息

Microbiol Resour Announc. 2020 Jan 23;9(4):e01404-19. doi: 10.1128/MRA.01404-19.

DOI:10.1128/MRA.01404-19
PMID:31974155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6979304/
Abstract

Extensively drug-resistant (XDR) has become a challenge to the treatment of tuberculosis (TB) in several countries, including Nepal. Here, we report for the first time the draft genome sequence of an isolate of XDR-TB collected in Nepal and describe single-nucleotide variations associated with its extensively drug-resistant phenotype.

摘要

广泛耐药结核(XDR)已成为包括尼泊尔在内的多个国家结核病治疗面临的一项挑战。在此,我们首次报告了在尼泊尔收集的一株广泛耐药结核分枝杆菌分离株的基因组草图序列,并描述了与其广泛耐药表型相关的单核苷酸变异。