Gautam Sanjay S, Leong Kelvin W C, Pradhan Manoj, Singh Y Ibotomba, Rajbhandari Sagar K, Ghimire Gokarna R, Adhikari Krishna, Shrestha Uma, Chaudhary Raina, Ghimire Gyanendra, Khadka Sundar, O'Toole Ronan F
School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.
School of Molecular Sciences, College of Science, Health and Engineering, La Trobe University, Victoria, Australia.
Microbiol Resour Announc. 2020 Jan 23;9(4):e01404-19. doi: 10.1128/MRA.01404-19.
Extensively drug-resistant (XDR) has become a challenge to the treatment of tuberculosis (TB) in several countries, including Nepal. Here, we report for the first time the draft genome sequence of an isolate of XDR-TB collected in Nepal and describe single-nucleotide variations associated with its extensively drug-resistant phenotype.
广泛耐药结核(XDR)已成为包括尼泊尔在内的多个国家结核病治疗面临的一项挑战。在此,我们首次报告了在尼泊尔收集的一株广泛耐药结核分枝杆菌分离株的基因组草图序列,并描述了与其广泛耐药表型相关的单核苷酸变异。