Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.
Department of Neurodegeneration, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
J Neurol. 2018 Mar;265(3):717-727. doi: 10.1007/s00415-017-8652-3. Epub 2017 Nov 2.
The emerging understanding of molecular changes in a wide range of brain tumours has led to a significant shift in how these tumours are diagnosed, managed and treated. This article will provide a hands-on overview of the relevant biomarkers and their association with newly defined biological tumour entities.
对广泛的脑肿瘤分子变化的新认识,导致了这些肿瘤的诊断、管理和治疗方式的重大转变。本文将提供相关生物标志物及其与新定义的生物学肿瘤实体的关联的实用概述。