Jacoby Adam, Stranix John T, Cohen Oriana, Louie Eddie, Balsam Leora B, Levine Jamie P
Hansjörg Wyss Department of Plastic Surgery, NYU Langone Medical Center, New York, New York.
Division of Infectious Diseases & Immunology, Department of Medicine, NYU Langone Medical Center, New York, New York.
J Card Surg. 2017 Nov;32(11):732-737. doi: 10.1111/jocs.13230. Epub 2017 Nov 3.
Left ventricular assist devices (LVADs) have become useful adjuncts in the treatment of patients with end-stage heart failure. LVAD implantation is associated with a unique set of problems; one such problem is device infection. We report our experience with flap salvage of infected and/or exposed LVAD hardware.
Between 2011 and 2016, 49 patients underwent LVAD implantation at our institution. Patients were then categorized by infectious status: systemic infection not directly involving the LVAD device, hardware infection responsive to antibiotics, and exposure of LVAD hardware or device infection refractory to antibiotics requiring debridement and flap coverage.
Approximately 50% of device-related infections resolved with either oral or intravenous antibiotics while the other 50% necessitated debridement and coverage with healthy tissue. In total, 12 patients (24%) developed a device-related infection ranging from superficial driveline cellulitis to purulent pocket infections. Seven patients (14%) required extensive debridement and/or flap coverage.
Early debridement and coverage of exposed hardware are crucial to successfully treating these LVAD infections.
左心室辅助装置(LVAD)已成为终末期心力衰竭患者治疗中的有用辅助手段。LVAD植入与一系列独特的问题相关;其中一个问题是装置感染。我们报告了我们在挽救感染和/或暴露的LVAD硬件方面的皮瓣修复经验。
2011年至2016年期间,49例患者在我们机构接受了LVAD植入。然后根据感染状况对患者进行分类:未直接累及LVAD装置的全身感染、对抗生素有反应的硬件感染,以及LVAD硬件暴露或对抗生素难治的装置感染,需要清创和皮瓣覆盖。
约50%的与装置相关的感染通过口服或静脉使用抗生素得到解决,而另外50%需要清创并用健康组织覆盖。总共有12例患者(24%)发生了与装置相关的感染,范围从浅表驱动线蜂窝织炎到脓性腔隙感染。7例患者(14%)需要广泛清创和/或皮瓣覆盖。
早期清创和覆盖暴露的硬件对于成功治疗这些LVAD感染至关重要。