Hou Lisha, Du Xudong, Chen Longmei, Li Jijie, Yan Peijing, Zhou Muke, Zhu Cairong
a Department of Epidemiology and Biostatistics, West China School of Public Health , Sichuan University , Chengdu , Sichuan , China.
b National Clinical Research Center for Geriatrics, West China Hospital , Sichuan University , Chengdu , Sichuan , China.
Int J Neurosci. 2018 Jun;128(6):540-548. doi: 10.1080/00207454.2017.1400971. Epub 2017 Nov 20.
Quality of life (QoL) post-stroke is an important health outcome. Physical deconditioning and physical inactivity are highly prevalent in stroke survivors. This study aimed to assess the long-term trends in QoL and to explore the effect of exercise on the QoL of ischaemic stroke patients.
Data for this prospective study were collected at baseline using face-to-face interviews, and telephone follow-ups were completed every three months from 2010 through 2014. QoL was evaluated with the 12-item Short-Form Health Survey (SF-12). The relationship between changes in exercise and QoL changes was analysed with a multi-level model.
Exercise and QoL generally increased during the study period. After adjusting for covariates, the SF-12 Physical Component Summary (PCS) scores increased by 0.60 on average for each unit increase in exercise frequency and by 0.52 for each hour increase in weekly exercise time. For weekly exercise times ≤ 22.73 h, the PCS scores continued to increase with increasing exercise time. The Mental Component Summary scores increased by 0.51 on average for each unit increase in exercise frequency and by 0.35 for each hour increase in weekly exercise time. Furthermore, the standard deviations of exercise frequency and exercise time were inversely associated with changes in the PCS score.
Exercise is an important modifiable behaviour. Long-term regular mild exercise should be recommended to improve QoL among stroke survivors.
中风后的生活质量（QoL）是一项重要的健康指标。身体机能衰退和缺乏身体活动在中风幸存者中极为普遍。本研究旨在评估生活质量的长期趋势，并探讨运动对缺血性中风患者生活质量的影响。
本前瞻性研究的数据在基线时通过面对面访谈收集，并于2010年至2014年期间每三个月完成一次电话随访。使用12项简短健康调查问卷（SF-12）评估生活质量。采用多层次模型分析运动变化与生活质量变化之间的关系。
在研究期间，运动和生活质量总体上有所提高。在调整协变量后，运动频率每增加一个单位，SF-12身体成分总结（PCS）得分平均增加0.60，每周运动时间每增加一小时，得分增加0.52。对于每周运动时间≤22.73小时的情况，PCS得分随着运动时间的增加而持续上升。运动频率每增加一个单位，心理成分总结得分平均增加0.51，每周运动时间每增加一小时，得分增加0.35。此外，运动频率和运动时间的标准差与PCS得分的变化呈负相关。
运动是一种重要的可改变行为。应建议长期进行规律的轻度运动，以提高中风幸存者的生活质量。
