West China School of Public Health and West China Fourth Hospital, Sichuan University, No. 17 Section 3, Renmin South Road, Chengdu, 610041, Sichuan, China.
National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Sci Rep. 2021 Jun 28;11(1):13372. doi: 10.1038/s41598-021-92736-5.
The relationship between exercise and stroke recurrence is controversial. This study was designed to test whether an association exists between exercise and ischemic stroke recurrence in first-ever ischemic stroke survivors. Data were collected from January 2010 to June 2016. Baseline information was obtained during face-to-face interviews, and follow-up phone interviews were conducted every 3 months. Exercise type, frequency, intensity, and duration were recorded. Discrete-time survival analysis was used to determine the relationship between exercise and stroke recurrence. 760 first-ever ischemic stroke survivors who were able to exercise were enrolled. After adjusting for covariates, patients who exercised 3.5-7 h per week and more than 7 h per week had a lower relapse risk than patients who did not exercise (3.5-7: OR 0.415; > 7: OR 0.356). Moreover, if the fluctuation of exercise duration was over 4 h, the patients had a higher risk of stroke recurrence than those with variability of less than 2 h (OR 2.153, P = 0.013). Stroke survivors who engage in long-term regular mild exercise (more than 5 sessions per week and lasting on average 40 min per session) have a lower recurrence rate. Irregular exercise increases the risk of stroke recurrence.
运动与中风复发的关系存在争议。本研究旨在检验首次缺血性中风幸存者的运动与缺血性中风复发之间是否存在关联。数据收集于 2010 年 1 月至 2016 年 6 月。基线信息通过面对面访谈获得，每 3 个月进行一次随访电话访谈。记录运动类型、频率、强度和持续时间。离散时间生存分析用于确定运动与中风复发之间的关系。纳入了 760 名能够运动的首次缺血性中风幸存者。调整协变量后，每周运动 3.5-7 小时和每周运动超过 7 小时的患者复发风险低于不运动的患者（3.5-7：OR 0.415；>7：OR 0.356）。此外，如果运动持续时间的波动超过 4 小时，患者中风复发的风险高于波动小于 2 小时的患者（OR 2.153，P=0.013）。长期定期进行轻度运动（每周超过 5 次，每次平均持续 40 分钟）的中风幸存者复发率较低。不规律的运动增加了中风复发的风险。
