Ha William N, Nicholson Timothy, Kahler Bill, Walsh Laurence J
School of Dentistry, University of Queensland, Herston, Brisbane 4004, Australia.
School of Chemical Engineering, University of Queensland, St. Lucia, Brisbane 4067, Australia.
Materials (Basel). 2017 Nov 2;10(11):1261. doi: 10.3390/ma10111261.
Mineral trioxide aggregate (MTA) restoratives and MTA sealers are commonly used in endodontics. Commonly referenced standards for testing of MTA are ISO 6876, 9917-1 and 10993. A PubMed search was performed relating to the relevant tests within each ISO and "mineral trioxide aggregate". MTA restoratives are typically tested with a mixture of tests from multiple standards. As the setting of MTA is dependent upon hydration, the results of various MTA restoratives and sealers are dependent upon the curing methodology. This includes physical properties after mixing, physical properties after setting and biocompatibility. The tests of flow, film thickness, working time and setting time can be superseded by rheology as it details how MTA hydrates. Physical property tests should replicate physiological conditions, i.e. 37 °C and submerged in physiological solution. Biocompatibility tests should involve immediate placement of samples immediately after mixing rather than being cured prior to placement as this does not replicate clinical usage. Biocompatibility tests should seek to replicate physiological conditions with MTA tested immediately after mixing.
三氧化矿物凝聚体（MTA）修复材料和MTA封闭剂常用于牙髓病学。常用于测试MTA的标准是ISO 6876、9917 - 1和10993。在PubMed上进行了与每个ISO标准内的相关测试以及“三氧化矿物凝聚体”相关的检索。MTA修复材料通常采用来自多个标准的测试组合进行测试。由于MTA的凝固取决于水合作用，各种MTA修复材料和封闭剂的结果取决于固化方法。这包括混合后的物理性能、凝固后的物理性能和生物相容性。流动度、薄膜厚度、工作时间和凝固时间的测试可以被流变学所取代，因为流变学详细说明了MTA的水合作用方式。物理性能测试应模拟生理条件，即37°C并浸没在生理溶液中。生物相容性测试应在混合后立即放置样品，而不是在放置前进行固化，因为这不能模拟临床使用情况。生物相容性测试应设法在混合后立即对MTA进行测试，以模拟生理条件。
