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非创伤性急诊剖腹手术:是否需要采用与创伤手术相似的手术原则?

Nontraumatic Emergency Laparotomy: Surgical Principles Similar to Trauma Need to Be Adopted?

作者信息

Singh-Ranger Deepak, Leung Edmund, Lau-Robinson Mei-Ling, Ramcharan Sean, Francombe James

机构信息

From the Warwick Hospital, Warwick, United Kingdom.

出版信息

South Med J. 2017 Nov;110(11):688-693. doi: 10.14423/SMJ.0000000000000721.

Abstract

OBJECTIVES

In 2011, the Royal College of Surgeons published in response to variable clinical outcomes for emergency surgery. The purpose of this study was to examine whether different treatment modalities would alter survival.

METHODS

All patients who underwent emergency laparotomy between April 2011 and December 2012 at Warwick Hospital (Warwick, UK) were included retrospectively. Information relating to their demographics; preoperative score; primary pathology; timing of surgery; intraoperative details; and postoperative outcome, including 30-day mortality, were collated for statistical analysis.

RESULTS

In total, 91 patients underwent 97 operations. The median age was 64 years (range 50-90, male:female 1:2). Sixty-five percent of cases were obstruction and perforation, and 66% of all operations were performed during office hours. The unadjusted 30-day mortality was 15.4%. Compared with nonsurvivors, survivors had a significantly higher Portsmouth-Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity score ( < 0.001), prolonged duration of hypotension and use of inotropes ( = 0.013), higher volume of colloid use ( = 0.04), and lower core body temperature ( < 0.05). Grades of surgeons did not influence mortality.

CONCLUSIONS

The 30-day mortality rate is comparable to the national standard. Further studies are warranted to determine whether trauma management modalities may be adopted to target high-risk patients who exhibit the lethal triad of hypotension, coagulopathy, and hypothermia.

摘要

目的

2011年,皇家外科医学院针对急诊手术中多变的临床结果发表了相关内容。本研究的目的是检验不同的治疗方式是否会改变生存率。

方法

回顾性纳入2011年4月至2012年12月在英国沃里克郡沃里克医院接受急诊剖腹手术的所有患者。收集有关他们的人口统计学信息、术前评分、主要病理、手术时间、术中细节以及术后结果(包括30天死亡率)的数据进行统计分析。

结果

共有91例患者接受了97次手术。中位年龄为64岁(范围50 - 90岁,男女比例为1:2)。65%的病例为梗阻和穿孔,66%的手术在办公时间进行。未经调整的30天死亡率为15.4%。与非幸存者相比,幸存者的朴茨茅斯生理和手术严重程度评分(用于死亡率和发病率的枚举)显著更高(<0.001),低血压持续时间和使用血管活性药物的时间更长(=0.013),胶体使用量更高(=0.04),核心体温更低(<0.05)。外科医生的级别不影响死亡率。

结论

30天死亡率与国家标准相当。有必要进一步研究是否可以采用创伤管理模式来针对出现低血压、凝血功能障碍和体温过低这一致死三联征的高危患者。

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