Leung Leslie T F, Papp Anthony
Division of Plastic & Reconstructive Surgery, University of British Columbia, Vancouver, B.C., Canada.
Division of Plastic & Reconstructive Surgery, University of British Columbia, Vancouver, B.C., Canada.
Burns. 2018 May;44(3):646-650. doi: 10.1016/j.burns.2017.10.010.
Accelerants are flammable substances that may cause explosion when added to existing fires. The relationships between drug abuse and accelerant-related burns are not well elucidated in the literature. Of these burns, a portion is related to drug manufacturing, which have been shown to be associated with increased burn complications.
Retrospective case control study. Patient data associated with accelerant-related burns from 2009 to 2014 were obtained from the British Columbia Burn Registry. These patients were compared with a control group of non-accelerant related burns. Clinical outcomes that were evaluated include inhalational injury, ICU length of stay, ventilator support, surgeries needed, and burn complications. Chi-square test was used to evaluate categorical data and Student's t-test was used to evaluate mean quantitative data with the p value set at 0.05. A logistic regression model was used to evaluate factors affecting burn complications.
Accelerant-related burns represented 28.2% of all burn admissions (N=532) from 2009 to 2014. The accelerant group had higher percentage of patients with history of drug abuse and was associated with higher TBSA burns, ventilator support, ICU stay and pneumonia rates compared to the non-accelerant group. Within the accelerant group, there was no difference in clinical outcomes amongst people with or without history of drug abuse. Four cases were associated with methamphetamine manufacturing, all of which underwent ICU stay and ventilator support.
Accelerant-related burns cause significant burden to the burn center. A significant proportion of these patients have history of drug abuse.
助燃剂是易燃物质，添加到现有火灾中可能会引发爆炸。药物滥用与助燃剂相关烧伤之间的关系在文献中尚未得到充分阐明。在这些烧伤中，一部分与药物制造有关，已显示出与烧伤并发症增加有关。
1）评估省级烧伤中心助燃剂相关烧伤的人口统计学和临床结局。2）将临床结局与非助燃剂相关烧伤的对照组进行比较。3）分析有药物滥用和药物制造史的患者亚组。
回顾性病例对照研究。从不列颠哥伦比亚省烧伤登记处获取2009年至2014年与助燃剂相关烧伤的患者数据。将这些患者与非助燃剂相关烧伤的对照组进行比较。评估的临床结局包括吸入性损伤、重症监护病房住院时间、呼吸机支持、所需手术和烧伤并发症。采用卡方检验评估分类数据，采用学生t检验评估平均定量数据，p值设定为0.05。采用逻辑回归模型评估影响烧伤并发症的因素。
2009年至2014年，助燃剂相关烧伤占所有烧伤入院病例的28.2%（N = 532）。与非助燃剂组相比，助燃剂组有药物滥用史的患者比例更高，且与更高的烧伤总面积、呼吸机支持、重症监护病房住院时间和肺炎发生率相关。在助燃剂组中，有无药物滥用史的患者临床结局无差异。有4例与甲基苯丙胺制造有关，所有这些患者都接受了重症监护病房住院治疗和呼吸机支持。
助燃剂相关烧伤给烧伤中心带来了沉重负担。这些患者中有很大一部分有药物滥用史。
