Chen Jiamin, Hua Yunfeng, Jiang Yangwei, Zhou Xiaolin, Zhang Linxi
Department of Physics, Zhejiang University, Hangzhou, 310027, China.
Sci Rep. 2017 Nov 3;7(1):15006. doi: 10.1038/s41598-017-15095-0.
We investigate the dynamics of two-dimensional soft vesicles filled with chiral active particles by employing the overdamped Langevin dynamics simulation. The unidirectional rotation is observed for soft vesicles, and the rotational angular velocity of vesicles depends mainly on the area fraction (ρ) and angular velocity (ω) of chiral active particles. There exists an optimal parameter for ω at which the rotational angular velocity of vesicle takes its maximal value. Meanwhile, at low concentration the continuity of curvature is destroyed seriously by chiral active particles, especially for large ω, and at high concentration the chiral active particles cover the vesicle almost uniformly. In addition, the center-of-mass mean square displacement for vesicles is accompanied by oscillations at short timescales, and the oscillation period of diffusion for vesicles is consistent with the rotation period of chiral active particles. The diffusion coefficient of vesicle decreases monotonously with increasing the angular velocity ω of chiral active particles. Our investigation can provide a few designs for nanofabricated devices that can be driven in a unidirectional rotation by chiral active particles or could be used as drug-delivery agent.
我们通过采用过阻尼朗之万动力学模拟来研究充满手性活性粒子的二维软囊泡的动力学。观察到软囊泡存在单向旋转，且囊泡的旋转角速度主要取决于手性活性粒子的面积分数（ρ）和角速度（ω）。对于ω存在一个最优参数，在此参数下囊泡的旋转角速度达到最大值。同时，在低浓度时，手性活性粒子会严重破坏曲率的连续性，尤其是对于大ω的情况，而在高浓度时，手性活性粒子几乎均匀地覆盖囊泡。此外，囊泡质心的均方位移在短时间尺度上伴有振荡，且囊泡扩散的振荡周期与手性活性粒子的旋转周期一致。囊泡的扩散系数随着手性活性粒子角速度ω的增加而单调减小。我们的研究可为纳米制造设备提供一些设计方案，这些设备可由手性活性粒子驱动进行单向旋转，或可用作药物递送剂。
