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肯塔基州综合性阿片类药物立法对一家城市急诊科中出现处方阿片类药物或海洛因滥用情况的患者的影响。

The Effects of Kentucky's Comprehensive Opioid Legislation on Patients Presenting with Prescription Opioid or Heroin Abuse to One Urban Emergency Department.

作者信息

Faryar Kiran A, Freeman Clifford L, Persaud Annuradha K, Furmanek Stephen P, Guinn Brian E, Mattingly William A, Wiemken Timothy L, Buckner Kimberley A, Huecker Martin R

机构信息

Department of Emergency Medicine, University of Louisville School of Medicine, Louisville, Kentucky.

Division of Infectious Diseases Clinical Research Support Program, University of Louisville School of Medicine, Louisville, Kentucky.

出版信息

J Emerg Med. 2017 Dec;53(6):805-814. doi: 10.1016/j.jemermed.2017.08.066. Epub 2017 Nov 6.

Abstract

BACKGROUND

Prescription opioid abuse has increased to epidemic proportions in the United States. Kentucky, along with other states, passed comprehensive legislation to monitor and curb opioid prescribing.

OBJECTIVES

This paper characterizes patients who presented to the emergency department (ED) after abusing prescription opioids and heroin prior to and after the passage of House Bill 1 (HB1) in April 2012.

METHODS

Based on a retrospective review of ED visits from 2009-2014 in one urban adult facility, patients were included if the chief complaint or diagnosis was directly related to prescription opioid or heroin abuse. The primary outcome is the number and type of substance abused by each ED patient.

RESULTS

From 2009-2014, 2945 patients presented to the ED after prescription opioid or heroin abuse. The number of prescription opioid patients decreased from 215 (of 276 patients) in 2009 to 203 (of 697 patients) in 2014; 77.9% of patients abused opioids in 2009, vs. 29% in 2014 (a 63% decrease). The number of heroin patients increased from 61 in 2009 to 494 in 2014; 22% of patients in 2009 abused heroin, vs. 71% in 2014 (a 221% increase). Both piecewise regression and autoregressive integrated moving average trend models showed an increased trend in patient heroin abuse beginning in 2011-2012.

CONCLUSIONS

Our facility experienced a decrease in the number of patients who abused prescription opioids and an increase in the number of patients who abused heroin over the study period. The transition seemed to occur just prior to, or concurrent with, enforcement of statewide opioid legislation.

摘要

背景

在美国,处方阿片类药物滥用已达到流行程度。肯塔基州与其他州一道通过了全面立法,以监测和遏制阿片类药物的处方开具。

目的

本文描述了在2012年4月众议院法案1(HB1)通过之前和之后,因滥用处方阿片类药物和海洛因而前往急诊科(ED)就诊的患者特征。

方法

基于对一家城市成人医疗机构2009 - 2014年急诊科就诊情况的回顾性研究,若主要诉求或诊断与处方阿片类药物或海洛因滥用直接相关,则纳入该患者。主要结局是每位急诊科患者滥用的物质数量和类型。

结果

2009 - 2014年,有2945名患者在滥用处方阿片类药物或海洛因后前往急诊科就诊。处方阿片类药物患者数量从2009年的215例(共276例患者)降至2014年的203例(共697例患者);2009年77.9%的患者滥用阿片类药物,而2014年为29%(下降了63%)。海洛因患者数量从2009年的61例增至2014年的494例;2009年22%的患者滥用海洛因,而2014年为71%(增长了221%)。分段回归模型和自回归积分滑动平均趋势模型均显示,从2011 - 2012年开始,患者海洛因滥用呈上升趋势。

结论

在研究期间,我们的医疗机构中滥用处方阿片类药物的患者数量减少,而滥用海洛因的患者数量增加。这种转变似乎发生在全州阿片类药物立法实施之前或同时。

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