正常发情周期中小型微型猪体内前列腺素F诱导的回归现象
Regression Induced by Prostaglandin F in Microminipigs During the Normal Estrous Cycle.
作者信息
Noguchi Michiko, Hirata Masaya, Kawaguchi Hiroaki, Tanimoto Akihide
机构信息
Laboratory of Theriogenology, Department of Veterinary Medicine, Azabu University, Sagamihara, Japan.
Laboratory of Domestic Animal Internal Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Japan.
出版信息
In Vivo. 2017 Nov-Dec;31(6):1097-1101. doi: 10.21873/invivo.11175.
Induction of corpus luteum regression and subsequent estrus using prostaglandin F (PGF) in microminipigs was investigated. Microminipigs with normal estrous cycle were treated with PGF as 0.75 mg (0.75 PG group, n=3) or 1.5 mg (1.5 PG group, n=4) dinoprost injected into the vulva at 24-h intervals at 10 days after the onset of estrus (D0), D1 and D2. Three microminipigs were not treated (control group). The estrous interval in the 1.5 PG group was significantly shortened compared to the control and 0.75 PG groups. Plasma progesterone levels started to decline and reached the base line in the 1.5 PG group significantly faster than in the control group. In conclusion, we demonstrate that multiple PGF treatments can induce corpus luteum regression and estrous synchronization in female microminipigs.
研究了使用前列腺素F（PGF）诱导微型猪黄体退化及随后发情的情况。对具有正常发情周期的微型猪在发情开始后第10天（D0）、D1和D2，每隔24小时经外阴注射0.75毫克（0.75 PG组，n = 3）或1.5毫克（1.5 PG组，n = 4）氯前列醇进行PGF处理。三只微型猪未接受处理（对照组）。与对照组和0.75 PG组相比，1.5 PG组的发情间隔显著缩短。1.5 PG组血浆孕酮水平开始下降并显著快于对照组达到基线水平。总之，我们证明多次PGF处理可诱导雌性微型猪黄体退化和发情同步。
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