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阿尔茨海默病的遗传异质性:拥抱研究合作。

Genetic Heterogeneity of Alzheimer's Disease: Embracing Research Partnerships.

机构信息

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.

IRCCS Don Gnocchi, Florence, Italy.

出版信息

J Alzheimers Dis. 2018;62(3):903-911. doi: 10.3233/JAD-170570.

Abstract

Studies on the genetics of Alzheimer's disease (AD) have revealed the complexity and heterogeneity of the disease. All our studies have supported this evidence and contribute to the current understanding of the genetic architecture of AD. This report reviews the success of our investigations, focusing on the implications and importance of the genetics of AD, and demonstrates the relevance of research strategies embracing partnerships.

摘要

对阿尔茨海默病(AD)遗传的研究揭示了该疾病的复杂性和异质性。我们所有的研究都支持这一证据,并有助于当前对 AD 遗传结构的理解。本报告回顾了我们研究的成功之处,重点介绍了 AD 遗传学的意义和重要性,并展示了采用合作研究策略的相关性。

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