衰老理论与老年痴呆症的流行。
Theories of Aging and the Prevalence of Alzheimer's Disease.
机构信息
Laboratory of Physical Anthropology and Biomathematics, Department of Anatomy, Institute of Biomedical Science, Federal University of Alfenas, Alfenas, Brazil.
Department of Physiology, School of Medicine and Pharmaceutical Sciences, System Emotional Science, University of Toyama, Toyama, Japan.
出版信息
Biomed Res Int. 2019 Jun 16;2019:9171424. doi: 10.1155/2019/9171424. eCollection 2019.
OBJECTIVE
Aging and AD are associated in some way, then it is reasonable to ask whether or not it is possible to age without AD inexorably appearing at any moment, depending on the period of life. Therefore, the goal of this review is to verify, in light of some aging theories, the prevalence of AD.
METHODS
For the purpose of this manuscript, the indexers , , , and were considered; were researched. The research was conducted using PubMed, Medline, Scopus, Elsevier, and Google Scholar.
RESULTS
The most common subjects in the papers analyzed for this manuscript were aging and Alzheimer's disease. The association between Alzheimer and theories of aging seems inconclusive.
CONCLUSIONS
Accordingly, the general idea is that AD is associated with aging in such a way that almost all people will present this disease; however, it is plausible to consider that the increase in life expectancy will generate a high prevalence of AD. In a general sense, it seems that the theories of aging explain the origin of AD under superlative and catastrophic considerations and use more biomolecular data than social or behavioral data as the bases of analysis, which may be the problem.
目的
衰老是阿尔茨海默病（AD）的一个相关因素，那么我们有理由问，是否有可能在任何时刻都不会出现 AD 的情况下衰老，这取决于生命的阶段。因此，本综述的目的是根据一些衰老理论，验证 AD 的流行情况。
方法
为了撰写本文，考虑了索引词 、 、 、 ；检索了 。研究使用了 PubMed、Medline、Scopus、Elsevier 和 Google Scholar。
结果
本文分析的论文中最常见的主题是衰老和阿尔茨海默病。阿尔茨海默病与衰老理论之间的关联似乎没有定论。
结论
因此，一般的观点是，AD 与衰老有关，几乎所有人都会出现这种疾病；然而，考虑到预期寿命的延长将导致 AD 的高患病率是合理的。一般来说，衰老理论似乎以卓越和灾难性的考虑来解释 AD 的起源，并使用更多的生物分子数据而不是社会或行为数据作为分析的基础，这可能是问题所在。
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