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3
Nonalcoholic fatty liver disease: updates in noninvasive diagnosis and correlation with cardiovascular disease.非酒精性脂肪性肝病:非侵入性诊断的最新进展及其与心血管疾病的关联
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5
Correlation between liver fat content with dyslipidemia and Insulin resistance.肝脏脂肪含量与血脂异常及胰岛素抵抗之间的相关性。
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6
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10
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World J Gastroenterol. 2011 Jul 28;17(28):3335-41. doi: 10.3748/wjg.v17.i28.3335.

计算机断层扫描在沙特人群脂肪肝诊断及腹部脂肪分布中的应用

The Use of Computed Tomography in the Diagnosis of Fatty Liver and Abdominal Fat Distribution among a Saudi Population.

作者信息

Gasim Gasim Ibrahim, Elshehri Fahd Mohamed, Kheidr Mahmoud, Alshubaily Fahad Khalid, ElZaki ElZaki Mohamed, Musa Imad R

机构信息

Qassim College of Medicine, Qassim University, Saudi Arabia.

Suliman Alhabib Hospital, Buraidah, Saudi Arabia.

出版信息

Open Access Maced J Med Sci. 2017 Oct 14;5(6):762-765. doi: 10.3889/oamjms.2017.187. eCollection 2017 Oct 15.

DOI:10.3889/oamjms.2017.187
PMID:29104685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5661714/
Abstract

BACKGROUND

The pandemic of obesity is striking heavily worldwide and particularly among the affluent Gulf States where it is expected to continue to rise along with its complications.

AIM

To examine the link between liver fat infiltration and abdominal fat amount using plain computer-assisted tomography (CT).

METHODS

Fifty patients visiting the obesity clinic of "King Fahd Specialist Hospital" or Dr Suliman Alhabeeb Hospital between January 2015 and April 2016 were included. Liver and splenic attenuation dimensions were undertaken with three hepatic regions of interests (ROIs) and two ROIs from the spleen. The liver attenuation indices (LAIs) that were measured liver parenchymal attenuation (CTLP), liver/splenic attenuation ratio (LS ratio)and the (3) difference between liver and splenic attenuation (LS dif) and based on this LS dif The patients were grouped as LS dif greater or less than 5. Abdominal fat was evaluated utilising a 3 mm chop CT scan starting from the umbilicus; then computed by a workstation. The abdominal fat was classified as total fat (TF) and the sub-compartments of visceral adipose (fat) (VF), and subcutaneous fat (SF).

RESULTS

Twenty-six of the participants were males. The mean (SD) of the age and BMI was 48 (14.9) years and 32.05 (8.3) kg/m respectively. The BMI and body Wt had a moderate negative correlation with the liver attenuation indices CTLP, LS ratio, LS diff (r = -0.417, -0.277, -0.312 and 0.435, -0.297, -0.0297), respectively. A very strong negative correlation between fatty liver, LS ratio and CTLP was found (-0.709, -0.575) respectively.

CONCLUSION

Plain computed tomography can reliably be used as a survey device for fatty liver disease.

摘要

背景

肥胖症大流行在全球范围内造成严重影响,尤其是在富裕的海湾国家,预计肥胖及其并发症的发病率还将继续上升。

目的

使用普通计算机断层扫描(CT)检查肝脏脂肪浸润与腹部脂肪量之间的联系。

方法

纳入2015年1月至2016年4月期间在“法赫德国王专科医院”或苏利曼·阿勒哈比卜博士医院肥胖门诊就诊的50例患者。对肝脏和脾脏进行衰减测量,在肝脏设置三个感兴趣区(ROI),在脾脏设置两个ROI。测量肝脏衰减指数(LAI),即肝实质衰减(CTLP)、肝/脾衰减比(LS比值)以及肝与脾衰减之间的差值(LS差值),并基于此将患者分为LS差值大于或小于5两组。从脐部开始,使用3毫米层厚的CT扫描评估腹部脂肪,然后由工作站进行计算。腹部脂肪分为总脂肪(TF)、内脏脂肪(VF)和皮下脂肪(SF)亚组。

结果

26名参与者为男性。年龄和BMI的平均值(标准差)分别为48(14.9)岁和32.05(8.3)kg/m²。BMI和体重与肝脏衰减指数CTLP、LS比值、LS差值分别呈中度负相关(r分别为-0.417、-0.277、-0.312和0.435、-0.297、-0.0297)。脂肪肝与LS比值和CTLP之间分别存在非常强的负相关(-0.709、-0.575)。

结论

普通计算机断层扫描可可靠地用作脂肪肝疾病的筛查手段。