Grivaux M, Goupil F, Asselain B, Blanchon F, Collon T, Coëtmeur D, Dayen C, Locher C, Molinier O, Martin F, Debieuvre D
Service de pneumologie, centre hospitalier de Meaux, 77100 Meaux, France.
Service de pneumologie, centre hospitalier du Mans, 72000 Le Mans, France.
Rev Mal Respir. 2017 Nov;34(9):991-999. doi: 10.1016/j.rmr.2017.10.001. Epub 2017 Oct 27.
The objective of the ESCAP-2011-CPHG cohort study was to perform a real-life analysis of therapeutic strategies used during the first 2years of follow-up after a diagnosis of primary lung cancer. This paper presents the study and its first results in non-small-cell lung cancer (NSCLC).
Pulmonologists in the respiratory disease departments of 53 general hospitals consecutively included all patients aged 18years and over with lung cancer newly diagnosed in 2010.
Of the 3943 patients included, 3418 (mean age: 65.4 years; male: 76%; never smokers: 12%) had NSCLC (adenocarcinoma: 53%; stages 0-II, IIIA, IIIB and IV: 18, 14, 9 and 59%, respectively). Mean follow-up was 13.2 (SD: 10.1) months; mean number of strategies implemented was 2 (SD: 1.3). Overall, 62% of patients had chemotherapy in the first strategy (74% in the second strategy); the rate of chemotherapy alone increased from 6 to 56% with cancer stage.
ESCAP-2011-CPHG opens the way to many possible analyses of the therapeutic strategies currently implemented in French hospitals, comparing strategies, survival or patient characteristics.
ESCAP - 2011 - CPHG队列研究的目的是对原发性肺癌诊断后随访的前两年中所采用的治疗策略进行实际分析。本文介绍了该研究及其在非小细胞肺癌（NSCLC）方面的初步结果。
53家综合医院呼吸科的肺科医生连续纳入了2010年新诊断的所有18岁及以上的肺癌患者。
在纳入的3943例患者中，3418例（平均年龄：65.4岁；男性：76%；从不吸烟者：12%）患有非小细胞肺癌（腺癌：53%；0 - II期、IIIA期、IIIB期和IV期分别为18%、14%、9%和59%）。平均随访时间为13.2（标准差：10.1）个月；实施的策略平均数量为2（标准差：1.3）。总体而言，62%的患者在第一种策略中接受了化疗（第二种策略中为74%）；单纯化疗的比例随着癌症分期从6%增加到56%。
ESCAP - 2011 - CPHG为对法国医院目前实施的治疗策略进行多种可能的分析开辟了道路，包括比较策略、生存率或患者特征。
