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越桔渣对波兰美利奴羊和 Wrzosówka 羔羊血液和肝脏组织抗氧化参数的影响。

Chokeberry Pomace as a Determinant of Antioxidant Parameters Assayed in Blood and Liver Tissue of Polish Merino and Wrzosówka Lambs.

机构信息

Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, 05-552 Jastrzebiec, Poland.

Department of Pharmacognosy, University of Vienna, 1090 Vienna, Austria.

出版信息

Molecules. 2017 Nov 7;22(11):1461. doi: 10.3390/molecules22111461.

Abstract

Despite being a plant by-product, chokeberry pomace is believed to exert some therapeutic effects because it is one of the richest sources of highly bioavailable non-enzymatic antioxidants. The aim of this study was to determine the functionality of bioactive compounds present in the pomace (chokeberry) based on enzymatic and non-enzymatic parameters related to the active defence of liver and blood against the effects of oxidative stress. The experiment was conducted with 48 lambs of two breeds-Polish Merino and Wrzosówka. Experimental groups were administered the basic feed with the addition of 150 g or 300 g of black chokeberry pomace per each kg of the complete feed. The activities of antioxidative enzymes (superoxide dismutase, glutathione peroxidase), peptides (glutathione, glutathione disulfide), and a lipid peroxidation indicator (malondialdehyde), as well as the capacity of non-enzymatic antioxidants were investigated. The results proved a strong effect of bioactive compounds contained in the black chokeberry pomace on the estimated parameters. The inclusion of chokeberry pomace in feed mixtures brought many benefits linked with the antioxidative protection. Parameters responsible for the oxidative status were significantly modified despite the commonly-held view about a limited possibility of transferring phenolic compounds to the organs.

摘要

尽管黑果腺肋花楸渣是植物的副产品,但由于它是高生物利用度非酶抗氧化剂的最丰富来源之一,因此被认为具有一些治疗作用。本研究的目的是根据与肝脏和血液的主动防御免受氧化应激影响有关的酶促和非酶参数来确定渣(黑果腺肋花楸)中生物活性化合物的功能。该实验是在两个品种的 48 只羔羊(波兰美利奴羊和 Wrzosówka)中进行的。实验组用基础饲料喂养,并在每公斤全价饲料中添加 150 克或 300 克黑果腺肋花楸渣。研究了抗氧化酶(超氧化物歧化酶、谷胱甘肽过氧化物酶)、肽(谷胱甘肽、谷胱甘肽二硫化物)和脂质过氧化指标(丙二醛)的活性,以及非酶抗氧化剂的能力。结果证明了黑果腺肋花楸渣中所含生物活性化合物对估计参数的强烈影响。尽管普遍认为酚类化合物向器官转移的可能性有限,但在饲料混合物中添加黑果腺肋花楸渣带来了许多与抗氧化保护相关的好处。负责氧化状态的参数发生了显著变化。

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