Laboratório Multiusuário de Bioinformática, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG 35400-000, Brazil.
Departamento de Computação, Universidade Federal de Ouro Preto, Ouro Preto, MG 35400-000, Brazil.
Bioinformatics. 2018 Mar 15;34(6):1040-1042. doi: 10.1093/bioinformatics/btx714.
Information about metabolic pathways in a comparative context is one of the most powerful tool to help the understanding of genome-based differences in phenotypes among organisms. Although several platforms exist that provide a wealth of information on metabolic pathways of diverse organisms, the comparison among organisms using metabolic pathways is still a difficult task.
We present TabPath (Tables for Metabolic Pathway), a web-based tool to facilitate comparison of metabolic pathways in genomes based on KEGG. From a selection of pathways and genomes of interest on the menu, TabPath generates user-friendly tables that facilitate analysis of variations in metabolism among the selected organisms.
TabPath is available at http://200.239.132.160:8686.
在比较的背景下了解代谢途径的信息是帮助理解生物之间基于基因组的表型差异的最有力工具之一。尽管存在几个提供有关不同生物代谢途径的大量信息的平台,但使用代谢途径进行生物之间的比较仍然是一项艰巨的任务。
我们提出了 TabPath(代谢途径表),这是一种基于 KEGG 的有助于比较基因组中代谢途径的网络工具。从菜单中选择感兴趣的途径和基因组,TabPath 生成用户友好的表格,便于分析所选生物之间的代谢变化。
TabPath 可在 http://200.239.132.160:8686 上获得。