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小梁切除术在改善青光眼患者生活质量方面的作用。

The role of trabeculectomy in enhancing glaucoma patient's quality of life.

作者信息

Binibrahim Ibrahim H, Bergström Anders K

机构信息

Department of Ophthalmology, Jeddah Eye Hospital, Jeddah, Saudi Arabia.

Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, Gothenburg, Sweden.

出版信息

Oman J Ophthalmol. 2017 Sep-Dec;10(3):150-154. doi: 10.4103/ojo.OJO_61_2016.

Abstract

PURPOSE

Is to control intraocular pressure (IOP) (up to 21 mmHg), to decrease medical treatment after trabeculectomy and to slow down or stop progression and deterioration in visual fields in glaucoma patients.

METHODS

A retrospective study. The charts of all trabeculectomies done in the Department of Ophthalmology at the Skåne University Hospital, Sweden during 2010 were retrospectively evaluated. The study was performed during fall 2012, so the longest follow-up is almost 2 years.

RESULTS

In total, 38 patients (21 males and 17 females) underwent trabeculectomy. The IOP was measured in both visits (pre- and post-operative); with a difference of -15.49 mmHg (-50.09%) respectively, showing a very highly statistical significance ( < 0.001). The amount of antiglaucoma drops was measured before and after the trabeculectomy, of average 3.5 drops and 1.2 drops, respectively. Showing a -2.30 difference (-66.41%), illustrating a very highly statistical significant value ( < 0.001). From 36 patients, 17 patients (45%) took Diamox before trabeculectomy, whereas 19 patients (50%) did not. After the trabeculectomy, only 1 patient (3%) took Diamox and 35 patients (92%) stopped taking Diamox, showing a very highly significant statistical value ( < 0.001). The visual field was measured for 13 patients showing a difference of -13.22 (-21.86%) before and after the trabeculectomy.

CONCLUSION

Trabeculectomy showed very high statistical significant results regarding IOP reduction and decrease in the amount of topical and systemic antiglaucoma medications.

摘要

目的

控制眼压(IOP)(高达21mmHg),减少小梁切除术后的药物治疗,并减缓或阻止青光眼患者视野的进展和恶化。

方法

一项回顾性研究。对2010年瑞典斯科讷大学医院眼科进行的所有小梁切除术病历进行回顾性评估。该研究于2012年秋季进行,因此最长随访时间近2年。

结果

共有38例患者(21例男性和17例女性)接受了小梁切除术。在两次就诊时(术前和术后)均测量了眼压;差异分别为-15.49mmHg(-50.09%),显示出非常高的统计学显著性(<0.001)。在小梁切除术前后测量了抗青光眼滴眼液的用量,平均分别为3.5滴和1.2滴。差异为-2.30(-66.41%),显示出非常高的统计学显著性值(<0.001)。在36例患者中,17例患者(45%)在小梁切除术前行乙酰唑胺治疗,而19例患者(50%)未使用。小梁切除术后,只有1例患者(3%)使用乙酰唑胺,35例患者(92%)停止使用乙酰唑胺,显示出非常高的统计学显著性(<0.001)。对13例患者进行了视野测量,小梁切除术前后差异为-13.22(-21.86%)。

结论

小梁切除术在降低眼压以及减少局部和全身抗青光眼药物用量方面显示出非常高的统计学显著性结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee03/5657155/97d29ad63cc5/OJO-10-150-g003.jpg

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