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美国成年人中开角型青光眼的患病率。

Prevalence of open-angle glaucoma among adults in the United States.

作者信息

Friedman David S, Wolfs Roger C W, O'Colmain Benita J, Klein Barbara E, Taylor Hugh R, West Shelia, Leske M Cristina, Mitchell Paul, Congdon Nathan, Kempen John

机构信息

Data Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD 21287, USA.

出版信息

Arch Ophthalmol. 2004 Apr;122(4):532-8. doi: 10.1001/archopht.122.4.532.

Abstract

OBJECTIVE

To estimate the prevalence and distribution of open-angle glaucoma (OAG) in the United States by age, race/ethnicity, and gender.

METHODS

Summary prevalence estimates of OAG were prepared separately for black, Hispanic, and white subjects in 5-year age intervals starting at 40 years. The estimated rates were based on a meta-analysis of recent population-based studies in the United States, Australia, and Europe. These rates were applied to 2000 US census data and to projected US population figures for 2020 to estimate the number of the US population with OAG.

RESULTS

The overall prevalence of OAG in the US population 40 years and older is estimated to be 1.86% (95% confidence interval, 1.75%-1.96%), with 1.57 million white and 398 000 black persons affected. After applying race-, age-, and gender-specific rates to the US population as determined in the 2000 US census, we estimated that OAG affects 2.22 million US citizens. Owing to the rapidly aging population, the number with OAG will increase by 50% to 3.36 million in 2020. Black subjects had almost 3 times the age-adjusted prevalence of glaucoma than white subjects.

CONCLUSIONS

Open-angle glaucoma affects more than 2 million individuals in the United States. Owing to the rapid aging of the US population, this number will increase to more than 3 million by 2020.

摘要

目的

按年龄、种族/族裔和性别估算美国开角型青光眼(OAG)的患病率及分布情况。

方法

分别针对40岁及以上的黑人、西班牙裔和白人受试者,以5岁为间隔进行OAG患病率汇总估算。估算率基于对美国、澳大利亚和欧洲近期基于人群研究的荟萃分析。这些率应用于2000年美国人口普查数据以及2020年美国预计人口数字,以估算美国患有OAG的人口数量。

结果

据估计,40岁及以上美国人群中OAG的总体患病率为1.86%(95%置信区间,1.75%-1.96%),其中157万白人和39.8万黑人患病。将种族、年龄和性别特异性率应用于2000年美国人口普查确定的美国人口后,我们估计OAG影响222万美国公民。由于人口迅速老龄化,到2020年,OAG患者数量将增加50%,达到336万。黑人受试者青光眼的年龄调整患病率几乎是白人受试者的3倍。

结论

在美国,开角型青光眼影响超过200万人。由于美国人口迅速老龄化,到2020年,这一数字将增至300多万。

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