Alnawaiseh Maged, Hömberg Lisann, Eter Nicole, Prokosch Verena
Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany.
Department of Ophthalmology, University of Mainz, Mainz, Germany.
J Ophthalmol. 2017;2017:8014294. doi: 10.1155/2017/8014294. Epub 2017 Oct 8.
To compare the structure-function relationships between retinal nerve fiber layer thickness (RNFLT) and visual field defects measured either by standard automated perimetry (SAP) or by Pulsar perimetry (PP).
263 eyes of 143 patients were prospectively included. Depending on the RNFLT, patients were assigned to the glaucoma group (group A: RNFL score 3-6) or the control group (group B: RNFL score 0-2). Structure-function relationships between RNFLT and mean sensitivity (MS) measured by SAP and PP were analyzed.
Throughout the entire group, the MS assessed by PP and SAP correlated significantly with RNFLT in all sectors. In the glaucoma group, there was no significant difference between the correlations RNFL-SAP and RNFL-PP, whereas a significant difference was found in the control group.
In the control group, the correlation between structure and function based on the PP data was significantly stronger than that based on SAP.
比较视网膜神经纤维层厚度(RNFLT)与通过标准自动视野计(SAP)或脉冲星视野计(PP)测量的视野缺损之间的结构-功能关系。
前瞻性纳入143例患者的263只眼。根据RNFLT,将患者分为青光眼组(A组:RNFL评分3-6)或对照组(B组:RNFL评分0-2)。分析了RNFLT与通过SAP和PP测量的平均敏感度(MS)之间的结构-功能关系。
在整个研究组中,通过PP和SAP评估的MS在所有象限均与RNFLT显著相关。在青光眼组中,RNFL-SAP和RNFL-PP之间的相关性无显著差异,而在对照组中发现了显著差异。
在对照组中,基于PP数据的结构与功能之间得相关性显著强于基于SAP的相关性。