Schrenzel Jacques, Lazarevic Vladimir
Laboratoire de recherche génomique, Service des maladies infectieuses, Département des spécialités de médecine, HUG, 1211 Genève 14.
Laboratoire de bactériologie, Service de médecine de laboratoire, Département de médecine génétique et de laboratoire, HUG, 1211 Genève 14.
Rev Med Suisse. 2017 Nov 8;13(582):1959-1961.
Due to technological advances in DNA sequencing, the number of microbiota studies has increased exponentially in recent years. The intestinal microbiota, characterized by high diversity and bacterial richness, received particular interest. The studies showed that the modifications of the intestinal microbiota derive from and lead to different mechanisms and explain various pathologies, including those outside the digestive system.The aim of this short article is to comment on some recent findings on the human microbiota in a clinical context. We attempt to identify the strengths of current research as well as the trends that emerge from an abundant literature of a rather heterogeneous quality.
由于DNA测序技术的进步，近年来微生物群研究的数量呈指数级增长。具有高度多样性和细菌丰富度特征的肠道微生物群受到了特别关注。研究表明，肠道微生物群的改变源于并导致不同的机制，解释了各种病理状况，包括消化系统以外的病理状况。这篇短文的目的是在临床背景下对人类微生物群的一些最新发现进行评论。我们试图确定当前研究的优势以及从大量质量参差不齐的文献中呈现出的趋势。
